Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Reevaluating streamflow declines across the middle East and central Asia with insights from change point detection. [PDF]
Dariane AB, Ghasemi M.
europepmc +1 more source
Tracing Cognitive Processes in Insight Problem Solving: Using GAMs and Change Point Analysis to Uncover Restructuring. [PDF]
Graf M, Danek AH, Vaci N, Bilalić M.
europepmc +1 more source
3D urban object change detection from aerial and terrestrial point clouds: A review
Wen Xiao +4 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Software belief reliability growth model incorporating change point and imperfect debugging based on uncertain differential equation approach. [PDF]
Sharma N +5 more
europepmc +1 more source
A change-point regression approach for estimating no observed adverse effect level from systematic review. [PDF]
Kuramochi Y, Hayamizu K.
europepmc +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Multiple change point analysis and time series forecast of brucellosis reports in Xinjiang, China from 2010 to 2024. [PDF]
Yang L +6 more
europepmc +1 more source

