Results 121 to 130 of about 961,218 (296)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Online Meta-Recommendation of CUSUM Hyperparameters for Enhanced Drift Detection
SensorsWith the increasing demand for time-series analysis, driven by the proliferation of IoT devices and real-time data-driven systems, detecting change points in time series has become critical for accurate short-term prediction.
Jessica Fernandes Lopes +2 more
doaj +1 more source
Multi-spectral and digital elevation model information fusion for automatic 3d change detection
, 2011 Various 2D and 3D change detection techniques have been developed in the literature to monitor changes inside urban areas. Nevertheless, most of theses techniques require the interaction of the user either to input data, set parameters, or to train ...
Chaabouni-Chouayakh, Houda +2 more
core
Detection of Geometric Temporal Changes in Point Clouds
Computer Graphics Forum, 2015 AbstractDetecting geometric changes between two 3D captures of the same location performed at different moments is a critical operation for all systems requiring a precise segmentation between change and no‐change regions. Such application scenarios include 3D surface reconstruction, environment monitoring, natural events management and forensic ...
Palma G +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Transactions of the Japanese Society for Artificial Intelligence, 2020 Shogo Hayashi +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Change‐point models to estimate the limit of detection
Statistics in Medicine, 2013 In many biological and environmental studies, measured data is subject to a limit of detection. The limit of detection is generally defined as the lowest concentration of analyte that can be differentiated from a blank sample with some certainty. Data falling below the limit of detection is left censored, falling below a level that is easily quantified
May, Ryan C. +5 more
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Change Point Detection in Financial Market Using Topological Data Analysis
SystemsChange points caused by extreme events in global economic markets have been widely studied in the literature. However, existing techniques to identify change points rely on subjective judgments and lack robust methodologies.
Jian Yao +4 more
doaj +1 more source