Results 111 to 120 of about 961,218 (296)

Change Point Geometry for Change Detection in Surveillance Video [PDF]

, 2015
A change detection algorithm is proposed based on geometric descriptors of space-time appearance discontinuities in fixed camera video. At each pixel in a video frame, intensity subsequences with similar appearance are segmented using a Hidden Semi-Markov Model (HSMM).
Brandon A. Mayer, Joseph L. Mundy
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Change Point Detection in Trend of Mortality Data [PDF]

Mortality refers to death that occurs within a population. It is linked to many factors such as age, sex, race, occupation and social class. Change in the pattern of mortality trend can affect the population standards of living and health care. This
کاظم نژاد, انوشیروان, امانی, فیروز, حبیبی, رضا   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Bayesian change point detection-based method for rolling bearing remaining useful life prediction

Advances in Mechanical Engineering
Addressing the multi-stage characteristics of rolling bearing degradation with random change points, this paper proposes a novel method for predicting the Remaining Useful Life (RUL) of multi-stage degradation processes.
Wenping Lei, Wangshen Hao, Chenyang Li, Yifei Zhang   +3 more
doaj   +1 more source

Change-Point Detection in Multivariate Categorical Processes With Variable Selection

IEEE Access, 2019
Statistical process control (SPC) has been widely used to control and improve the quality of products in manufacturing processes. Currently, a limited number of schemes is available for change-point detection in multivariate categorical processes (MCPs),
Qing He, Weiyan Liu, Junjie Wang
doaj   +1 more source

Parametric change point detection with random occurrence of the change point

, 2022
We are concerned with the problem of detecting a single change point in the model parameters of time series data generated from an exponential family. In contrast to the existing literature, we allow that the true location of the change point is itself random, possibly depending on the data. Under the alternative, we study the case when the size of the
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source