Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Influence of mindfulness and coping flexibility in the early phases of burnout development in intensive care unit healthcare workers during the COVID-19 pandemic. [PDF]
Claverie D +9 more
europepmc +1 more source
Stabilité, changement social et séparatisme dans les sociétés développées : le cas québécois [PDF]
Sigler, John
core +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Déclinaisons géographiques du changement social en Iran
Amin Moghadam +2 more
doaj +1 more source
Decriminalization undone: Assessing the amendment to British Columbia's decriminalization of personal drug possession framework. [PDF]
Speed KA +4 more
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Changes in the prevalence and causes of vision impairment and coverage of services between 2008 and 2024 in Koulikoro, Mali: results from two cross-sectional studies. [PDF]
Pente V +9 more
europepmc +1 more source
Normalising the French presidency : explaining François Hollande’s victory [PDF]
Evans, JAJ
core

