Results 271 to 280 of about 233,902 (342)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Bridging the know-do gap: improved adolescent sexual and reproductive health and health information systems in West Africa and the Middle East. [PDF]

Reprod Health
Sinha C, Ingabire MG, Schryer-Roy AM.
europepmc   +1 more source

Anthropologie du changement social

Annuaire de l'EHESS, 2007
openaire   +5 more sources

Exploring Forms and Practices of Menstruation in the Changing Social System: A Study of Suryabinayak-05, Katunje, Bhaktapur

Laxmi Adhikari, Mahalaxmi Thapa
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Empowerment as a key mechanism for supporting changes in eating behaviors among disadvantaged immigrant women living with diabetes, obesity or hypertension: a realistic evaluation. [PDF]

Arch Public Health
Eïd J, Canu O, Maiga A, Cohen J, Hassambay R, Bennis FZ, Rwegera B, du Loû AD.   +7 more
europepmc   +1 more source

Effect of Disclosure and Social Support on Change in Childbearing Intentions among People Diagnosed With Hiv

, 2019
Lanre-Babalola F.O, Oke O.A Salami K
openalex   +1 more source

Building a New Understanding of Changing Patterns of Community Interaction, Social Behavior, and Conflicts of Interest: A Theoretical Study

Yotam Senis, Musa Ayorbaba, Alfando Luas
openalex   +2 more sources

Empowering organizations: Revealing their perceptions to adapt support programs [PDF]

, 2009
Coudel, Emilie, Faure, Guy, Le Coq, Jean-François, Maître d'Hôtel, Elodie   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source