Results 111 to 120 of about 177,628,905 (262)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Preliminary Studies on the Distribution of Stable Pb and Pb-210 in the Maternal and Fetal Portions of Human Placentas

Brazilian Journal of Radiation Sciences
Fetal growth and survival are solely dependent on the placenta, making the characterization of toxic elements in this tissue crucial for understanding exposure during pregnancy.
Laíssa Adriana Bonifacio, Nathália Villa dos Santos, Naomi Akiba, Maciel Santos Luz, Rossana Pulcineli Vieira Francisco, Barbara Paci Mazzilli   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Reconnecting with the Self and Fetus through Mindfulness: Supporting Inner Balance and Bonding during Pregnancy

Psikiyatride Güncel Yaklaşımlar
Pregnancy is a complex period during which women experience profound physical, emotional, and social changes. Hormonal fluctuations, physiological transformations, and environmental factors during pregnancy can contribute to a range of psychosocial and ...
Ebru Sağıroğlu, Esmanur Körsü
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

INCOME, WEALTH, AND THE ECONOMIC WELL-BEING OF FARM HOUSEHOLDS [PDF]

Agricultural policy is rooted in the 1930s notion that providing transfers of money to the farm sector translates into increased economic well-being of farm families.
El-Osta, Hisham S., Johnson, James D., Hopkins, Jeffrey W., Mishra, Ashok K., Morehart, Mitchell J.   +4 more
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

The Impact of Oxidative Stress on the Epigenetics of Fetal Alcohol Spectrum Disorders

Antioxidants
Fetal alcohol spectrum disorders (FASD) represent a continuum of lifelong impairments resulting from prenatal exposure to alcohol, with significant global impact.
Sergio Terracina, Luigi Tarani, Mauro Ceccanti, Mario Vitali, Silvia Francati, Marco Lucarelli, Sabrina Venditti, Loredana Verdone, Giampiero Ferraguti, Marco Fiore   +9 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Psychology of Well-being. Theory, Research and Practice

, 2011
Psychology of Well-Being: Theory, Research and Practice is a peer-reviewed devoted to understanding the biopsychosocial and behavioural factors leading to enhanced well-being, optimal emotional processing and the prevention of psychological dysfunction ...
RUINI, CHIARA
core   +1 more source