Results 101 to 110 of about 3,122,392 (352)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Current Issues in Molecular BiologyRhythms, regulated by core clock genes like the period (per) gene family, are crucial for maintaining physiological processes in animals. In teleost fish, including channel catfish (Ictalurus punctatus), these genes have evolved distinct functions ...
Hongyan Liu +8 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Channel Estimation in OFDM Systems with Strong Interference [PDF]
, 2010 In this paper, we investigate channel estimation algorithms in an OFDM system which is exposed to pulsed interference. It will be examined how the interference affects the performance of the channel estimation and how the channel estimation can be ...
Epple, Ulrich, Schnell, Michael
core
Nitrogen and nitrification in the Houston Ship Channel
, 1977 169 pgs.The objective of this study was to investigate in detail the transport and interconversion of nitrogen forms in the Houston Ship Channel. Particular attention was given the process of nitrification, the bacterial oxidation of ammonia to nitrate ...
Tuffey, T.J. +2 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Social Sciences and Humanities OpenBackground: Medical cannabis (MC) patients in the United States navigate a fragmented legal landscape, with state laws ranging from prohibition to full legalization.
Thomas A. Clobes +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
KUTV news featurette on cloning, molecular genetics, and disease aired November 9, 1997
, 1997 videoThis 3 minutes, 1 second video clip from Salt Lake City\u27s KUTV, Channel 2 features a short interview with Mario Capecchi concerning cloning and its use in molecular genetics and the study of human ...
KUTV, Channel 2
core
Cultural incorporation of the Kirby-Bauer method in introductory microbiology lab
Journal of Microbiology & Biology EducationWith rising antibiotic resistance, researchers are exploring sourced pharmaceuticals from local plant materials. One avenue is medicinal plants used in Indigenous communities.
Ashley McCarley, Caryl Ann Becerra
doaj +1 more source