Results 101 to 110 of about 4,616,003 (296)

Artificial Intelligence for Venture Capital: Strategies Inspired by Financial and Manufacturing Industry Applications [PDF]

SHS Web of Conferences
The application of artificial intelligence (AI) in venture capital has gained significant attention as a means to improve risk assessment and decision-making. This study examines AI’s role in venture capital by analyzing its real-world implementations in
Gao Ke
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Analysis of the effect of the scorpion toxin AaH-II on action potential generation in the axon initial segment

Scientific Reports
The toxin AaH-II, from the scorpion Androctonus australis Hector venom, is a 64 amino acid peptide that targets voltage-gated Na+ channels (VGNCs) and slows their inactivation. While at macroscopic cellular level AaH-II prolongs the action potential (AP),
Fatima Abbas, Laila Ananda Blömer, Hugo Millet, Jérôme Montnach, Michel De Waard, Marco Canepari   +5 more
doaj   +1 more source

Molecular Characterization and Feeding-Associated Expression Dynamics of the Period Gene Family in Channel Catfish (Ictalurus punctatus)

Current Issues in Molecular Biology
Rhythms, regulated by core clock genes like the period (per) gene family, are crucial for maintaining physiological processes in animals. In teleost fish, including channel catfish (Ictalurus punctatus), these genes have evolved distinct functions ...
Hongyan Liu, Shiyong Zhang, Xiaohui Chen, Minghua Wang, Liqiang Zhong, Yongqiang Duan, Bingjie Xie, Luyu Tang, Yi Cheng   +8 more
doaj   +1 more source

Hotwater Geochemistry for Interpreting The Condition of Geothermal Reservoir, Dieng Plateau Case, Banjarnegara-Wonosobo Regency, Central Java

Indonesian Journal on Geoscience, 2014
DOI: 10.17014/ijog.v8i2.158The researched area, located in the Dieng Plateau, is included into the Holocene Dieng Volcanic Rock Unit. The regional structure in this area is originated from the major caldera with local fault having orientation of SE - NW.
Yuris Ramadhan, K. Channel, N. R. Herdianita   +2 more
doaj   +1 more source

The Binary Energy Harvesting Channel with a Unit-Sized Battery [PDF]

, 2014
We consider a binary energy harvesting communication channel with a finite-sized battery at the transmitter. In this model, the channel input is constrained by the available energy at each channel use, which is driven by an external energy harvesting ...
Ozel, Omur, Tutuncuoglu, Kaya, Ulukus, Sennur, Yener, Aylin   +3 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Carbonate chemistry of an in-situ free-ocean CO2 enrichment experiment (antFOCE) in comparison to short term variation in Antarctic coastal waters

Scientific Reports, 2018
Free-ocean CO2 enrichment (FOCE) experiments have been deployed in marine ecosystems to manipulate carbonate system conditions to those predicted in future oceans.
J. S. Stark, N. P. Roden, G. J. Johnstone, M. Milnes, J. G. Black, S. Whiteside, W. Kirkwood, K. Newbery, S. Stark, E. van Ooijen, B. Tilbrook, E. T. Peltzer, K. Berry, D. Roberts   +13 more
doaj   +1 more source

Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]

, 1988
We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source