Results 21 to 30 of about 3,122,392 (352)

Definition of two agonist types at the mammalian cold-activated channel TRPM8

eLife, 2016
Various TRP channels act as polymodal sensors of thermal and chemical stimuli, but the mechanisms whereby chemical ligands impact on TRP channel gating are poorly understood.
Annelies Janssens, Maarten Gees, Balazs Istvan Toth, Debapriya Ghosh, Marie Mulier, Rudi Vennekens, Joris Vriens, Karel Talavera, Thomas Voets   +8 more
doaj   +1 more source

Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Nature Communications, 2023
Glycine receptors are channel receptors mediating signal transduction between neurons that transit between resting and open states upon neurotransmitter binding.
Sophie Shi, Solène N. Lefebvre, Laurie Peverini, Adrien H. Cerdan, Paula Milán Rodríguez, Marc Gielen, Jean-Pierre Changeux, Marco Cecchini, Pierre-Jean Corringer   +8 more
doaj   +1 more source

VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8

Nature Communications, 2016
The temperature-sensitive TRPM8 channel is essential for cold sensing and has been linked to pathological cold hypersensitivity. Here, the authors find TRPM8 insertion in the cell membrane is mediated by VAMP7 following atypical LAMP1-containing vesicle ...
Debapriya Ghosh, Silvia Pinto, Lydia Danglot, Ine Vandewauw, Andrei Segal, Nele Van Ranst, Melissa Benoit, Annelies Janssens, Rudi Vennekens, Pieter Vanden Berghe, Thierry Galli, Joris Vriens, Thomas Voets   +12 more
doaj   +1 more source

Advanced Channel Estimation for MIMO-OFDM in Realistic Channel Conditions

, 2007
An advanced decision-directed channel estimation scheme is proposed, which is suitable for employment in a wide range of multi-antenna multi-carrier systems as well as for communications over the entire range of practical channel conditions.
Akhtman, J., L. Hanzo, Hanzo, L., J. Akhtman   +3 more
core   +2 more sources

Channel coding for satellite mobile channels [PDF]

International Journal of Satellite Communications, 1989
AbstractThe deployment of channel coding and interleaving to enhance the bit‐error performance of a satellite mobile radio channel is addressed for speech and data transmissions. Different convolutional codes (CC) using Viterbi decoding with soft decision are examined with inter‐block interleaving.
Wong, K H H, Hanzo, L, Steele, R
openaire   +1 more source

Functional expression of CLIFAHDD and IHPRF pathogenic variants of the NALCN channel in neuronal cells reveals both gain- and loss-of-function properties

Scientific Reports, 2019
The excitability of neurons is tightly dependent on their ion channel repertoire. Among these channels, the leak sodium channel NALCN plays a crucial role in the maintenance of the resting membrane potential.
Malik Bouasse, Hathaichanok Impheng, Zoe Servant, Philippe Lory, Arnaud Monteil   +4 more
doaj   +1 more source

Influencia del drenaje ácido de rocas producto del retroceso glaciar: hallazgos y propuestas de mitigación frente al cambio climático

South Sustainability
El cambio climático está intensificando la pérdida de glaciares en el Perú, lo que afecta de manera directa la calidad y disponibilidad del agua en las zonas altoandinas.
Channel Yurico Rodriguez-Torres
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Being Black in a Sea of Color: A Phenomenological Study Exploring Black Students’ Racial Experiences at an AANAPISI and Emerging HSI

Journal Committed to Social Change on Race and Ethnicity, 2019
This phenomenological study used semi-structured interviews with 13 Black college students attending a university that is both an Asian American Native American Pacific Islander Serving Institution (AANAPISI) and emerging Hispanic-Serving Institution ...
Charles Lu, Ajhanai Channel Inez Newton
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source