Results 91 to 100 of about 4,718,784 (295)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The control of attention to faces [PDF]

, 2007
Humans attend to faces. This study examines the extent to which attention biases to faces are under top-down control. In a visual cueing paradigm, observers responded faster to a target probe appearing in the location of a face cue than of a competing ...
Burton, A. Mike, Burton, A Mike, Schweinberger, Stefan R, Doherty, Martin J., Langton, Stephen R. H., Bindemann, Markus, Schweinberger, Stefan R., Doherty, Martin, Langton, Stephen   +8 more
core   +1 more source

Channel prior convolutional attention for medical image segmentation [PDF]

, 2023
Characteristics such as low contrast and significant organ shape variations are often exhibited in medical images. The improvement of segmentation performance in medical imaging is limited by the generally insufficient adaptive capabilities of existing ...
Huang, Hejun, Zou, Ying, Chen, Chaoyang, Lu, Ming, Chen, Zuguo   +4 more
core   +1 more source

Optimization and Application of Improved YOLOv9s-UI for Underwater Object Detection

Applied Sciences
The You Only Look Once (YOLO) series of object detection models is widely recognized for its efficiency and real-time performance, particularly under the challenging conditions of underwater environments, characterized by insufficient lighting and visual
Wei Pan, Jiabao Chen, Bangjun Lv, Likun Peng   +3 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Channel Recurrent Attention Networks for Video Pedestrian Retrieval

, 2021
Full attention, which generates an attention value per element of the input feature maps, has been successfully demonstrated to be beneficial in visual tasks.
Fang, Pengfei, Petersson, Lars, Jieming Zhou, Lars Petersson, Zhou, Jieming, Harandi, Mehrtash, Mehrtash Harandi, Pengfei Fang, Pan Ji, Ji, Pan   +9 more
core   +1 more source

Glaucoma Classification Using a NFNet-Based Deep Learning Model with a Customized Hybrid Attention Mechanism

Diagnostics
Background/Objectives: Glaucoma is a leading cause of irreversible blindness worldwide, making accurate and efficient detection methods essential. One primary concern with glaucoma is that it often presents no early symptoms. Vision loss typically begins
Sandeep Angara, Loc Tran, Jongwoo Kim
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source