Results 51 to 60 of about 290,361 (261)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Residual Channel Attention Network for Brain Glioma Segmentation

2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2022
A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning approaches have achieved outstanding performance in the automatic segmentation of brain glioma.
Yao, Yiming, Qian, Peisheng, Zhao, Ziyuan, Zeng, Zeng   +3 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Multiorder Attentional Spatial Interactive Convolutional Neural Network (MoAS-CNN) for Low-Resolution Haptic Recognition

Applied Sciences, 2022
In haptic recognition, pressure information is usually represented as an image, and then used for feature extraction and classification. Deep learning that processes haptic information in end-to-end manner has attracted attention.
Kailin Wen, Jie Chu, Yu Chen, Dong Liang, Chengkai Zhang, Jueping Cai   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

UWS-YOLO: Advancing Underwater Sonar Object Detection via Transfer Learning and Orthogonal-Snake Convolution Mechanisms

Journal of Marine Science and Engineering
Accurate and efficient detection of underwater targets in sonar imagery is critical for applications such as marine exploration, infrastructure inspection, and autonomous navigation.
Liang Zhao, Xu Ren, Lulu Fu, Qing Yun, Jiarun Yang   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

ICENETv2: A Fine-Grained River Ice Semantic Segmentation Network Based on UAV Images

Remote Sensing, 2021
Accurate ice segmentation is one of the most crucial techniques for intelligent ice monitoring. Compared with ice segmentation, it can provide more information for ice situation analysis, change trend prediction, and so on.
Xiuwei Zhang, Yang Zhou, Jiaojiao Jin, Yafei Wang, Minhao Fan, Ning Wang, Yanning Zhang   +6 more
doaj   +1 more source

MRI Reconstruction Via Cascaded Channel-Wise Attention Network [PDF]

2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), 2019
We consider an MRI reconstruction problem with input of k-space data at a very low undersampled rate. This can practically benefit patient due to reduced time of MRI scan, but it is also challenging since quality of reconstruction may be compromised. Currently, deep learning based methods dominate MRI reconstruction over traditional approaches such as ...
Huang, Qiaoying, Yang, Dong, Wu, Pengxiang, Qu, Hui, Yi, Jingru, Metaxas, Dimitris   +5 more
openaire   +2 more sources