Results 41 to 50 of about 338,609 (215)

Optimum response scheme of intrusion detection based on information theory

open access: yesTongxin xuebao, 2020
Intrusion detection system (IDS) often inevitably presents major security risks caused by FPs and FNs.However,at present,an effective solution has not been found.In order to solve this problem,an optimal response model of intrusion detection based on ...
Youliang TIAN, Yulong WU, Qiuxian LI
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Investigation of Underwater Wireless Optical Communication Channel Capacity for Different Environment and System Parameters

open access: yesHittite Journal of Science and Engineering, 2020
Underwater wireless optical communication (UWOC) systems using the blue / green bands of the visible light spectrum stand out as an important solution in underwater applications that require high data communication rate such as remote sensing and ...
Yiğit Mahmutoğlu   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

On Shannon’s Formula and Hartley’s Rule: Beyond the Mathematical Coincidence

open access: yesEntropy, 2014
In the information theory community, the following “historical” statements are generally well accepted: (1) Hartley did put forth his rule twenty years before Shannon; (2) Shannon’s formula as a fundamental tradeoff between transmission rate, bandwidth ...
Olivier Rioul , José Carlos Magossi
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

An Integer Erasure Correction Coding and Its Application for Security Enhancement of Encryption

open access: yesIEEE Access
This paper presents a new class of erasure-correcting codes (ECCs) aimed at enhancing cryptographic security of certain encryption schemes. The proposed ECCs employ integer arithmetic to encode and decode data bits and can correct all data bytes, each ...
Miodrag J. Mihaljevic   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy