Results 71 to 80 of about 1,404,609 (276)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Automated Selection of a Channel Subset Based on the Genetic Algorithm in a Motor Imagery Brain-Computer Interface System

IEEE Access, 2019
Brain-computer interface (BCI) is a system for communication and control between the human brain and computers or other electronic devices. However, multichannel signal acquisition, which is time-consuming, laborious, and not conducive to subsequent real-
Hongli Chang, Jimin Yang
doaj   +1 more source

Nonlinear Pattern Selection in Binary Mixture Convection with Through-Flow

, 2001
The pattern selection problem in binary-mixture convection in an extended channel with a lateral through-flow is presented. The through-flow breaks left--right parity and changes pattern dynamics dramatically.
Harada, Yoshifumi, Li, Guo-Dong, Ogawa, Atsushi, Tribelsky, Michael I.   +3 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Retrieval of Atmospheric Temperature and Humidity Profiles from FY-GIIRS Hyperspectral Data Using RBF Neural Network

Remote Sensing
Atmospheric temperature and humidity profiles are essential for numerical weather prediction and severe weather monitoring. To effectively utilize data from the Geostationary Interferometric Infrared Sounder (GIIRS) onboard the FY-4 satellite, this study
Shifeng Hao, Zhenshou Yu, Ziqi Jin
doaj   +1 more source

Overhead-Aware Distributed CSI Selection in the MIMO Interference Channel

, 2015
We consider a MIMO interference channel in which the transmitters and receivers operate in frequency-division duplex mode. In this setting, interference management through coordinated transceiver design necessitates channel state information at the ...
Bengtsson, Mats, Brandt, Rasmus, Ghauch, Hadi, Mochaourab, Rami   +3 more
core   +1 more source

Support Vector Channel Selection in BCI [PDF]

IEEE Transactions on Biomedical Engineering, 2004
Designing a brain computer interface (BCI) system one can choose from a variety of features that may be useful for classifying brain activity during a mental task. For the special case of classifying electroencephalogram (EEG) signals we propose the usage of the state of the art feature selection algorithms Recursive Feature Elimination and Zero-Norm ...
Lal, T., Schröder, M., Hinterberger, T., Weston, J., Bogdan, M., Birbaumer, N., Schölkopf, B.   +6 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

High-Q variable bandwidth passive filters for Software Defined Radio [PDF]

, 2001
An important aspect of Software Defined Radio is the ability to define the bandwidth of the filter that selects the desired channel. This paper describes a technique for channel filtering, in which two passive filters are combined to obtain a variable ...
Arkesteijn, Vincent J., Klumperink, Eric A.M., Nauta, Bram   +2 more
core   +5 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source