Results 181 to 190 of about 18,484 (195)

Acute Optogenetic Activation of the Subfornical Organ Produces Sympathetically Mediated Increases in Blood Pressure.

Neuroendocrinology
Van Acquoy ML, Nedelkoska T, McMullan S, Burke PGR, Hildreth CM.   +4 more
europepmc   +1 more source

Ca²⁺ signature-dependent control of auxin sensitivity in Arabidopsis

Song H, Baudon A, Freund M, Randuch M, Pěnčík A, Ondrej N, He Z, Kaufmann K, Gilliham M, Friml J, Hedrich R, Huang S.   +11 more
europepmc   +1 more source

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Light-gated channelrhodopsin sparks proton-induced calcium release in guard cells

Science, 2023
Although there has been long-standing recognition that stimuli-induced cytosolic pH alterations coincide with changes in calcium ion (Ca2+) levels, the interdependence between protons (H+) and Ca2+ remains poorly understood. We addressed this topic using
Shouguang Huang, Like Shen, M. Roelfsema, Dirk Becker, R. Hedrich   +4 more
semanticscholar   +1 more source

Twisting and Protonation of Retinal Chromophore Regulate Channel Gating of Channelrhodopsin C1C2.

Journal of the American Chemical Society, 2023
Channelrhodopsins (ChRs) are light-gated ion channels and central optogenetic tools that can control neuronal activity with high temporal resolution at the single-cell level.
Keisei Shibata, K. Oda, T. Nishizawa, Y. Hazama, Ryohei Ono, Shunki Takaramoto, R. Bagherzadeh, H. Yawo, O. Nureki, Keiichi Inoue, Hidefumi Akiyama   +10 more
semanticscholar   +1 more source

WormRuler: A software to track body length used to characterize a super red-shifted channelrhodopsin in Caenorhabditis elegans

microPublication Biology, 2022
Manipulation of neuronal or muscular activity by optogenetics or other stimuli can be directly linked to the analysis of Caenorhabditis elegans ( C. elegans ) body length. Thus, WormRuler was developed as an open-source video analysis toolbox that offers
Marius Seidenthal, Dennis Vettkötter, A. Gottschalk   +2 more
semanticscholar   +1 more source

Co-expressing fast channelrhodopsin with step-function opsin overcomes spike failure due to photocurrent desensitization in optogenetics: a theoretical study

Journal of Neural Engineering, 2022
Objective. A fundamental challenge in optogenetics is to elicit long-term high-fidelity neuronal spiking with negligible heating. Fast channelrhodopsins (ChRs) require higher irradiances and cause spike failure due to photocurrent desensitization under ...
Himanshu Bansal, Gur Pyari, Sukhdev Roy
semanticscholar   +1 more source

Electrostatic Control of Photoisomerization in Channelrhodopsin 2.

Journal of the American Chemical Society, 2021
Channelrhodopsin 2 (ChR2) is the most commonly used tool in optogenetics. Because of its faster photocycle compared to wild-type (WT) ChR2, the E123T mutant of ChR2 is a useful optogenetic tool when fast neuronal stimulation is needed.
Ruibin Liang, Jimmy K. Yu, J. Meisner, F. Liu, T. Martínez   +4 more
semanticscholar   +1 more source