Results 201 to 210 of about 129,105 (287)

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Role of MZB1 in disease pathogenesis: current insights and future directions. [PDF]

Clin Exp Med
Ding Y, Zhu M, Zhang R, Shao W, Chen M, Zhou G, Chang F.   +6 more
europepmc   +1 more source

Antioxidative and chaperone‐like activities of a bacterioruberin‐rich extract: An innovative approach to protect the skin proteome

International Journal of Cosmetic Science, EarlyView.
The bacteriorubin‐rich extract of Arthrobacter agilis has high antioxidative properties, protecting proteins against oxidative stress and preventing their carbonylation. It also protects proteins against saline and heat stresses, suggesting a dual mode of action including antioxidant and chaperone‐like activities.
Julie C. Tisserand, François‐Xavier Pellay, Nicolas Lecland, Arnaud Fontbonne, Félix Giraud, Eric Perrier, Sandra Trompezinski, Isabelle Benoit   +7 more
wiley   +1 more source

G4 Oligonucleotide-Based Chaperones of Heterogeneous Nuclear Ribonucleoprotein A1. [PDF]

Int J Mol Sci
Malakhova E, Svetlova J, Pavlova I, Alieva S, Severov V, Barinov N, Klinov D, Vedekhina T, Varizhuk A.   +8 more
europepmc   +1 more source

A Perspective From the British Society of Dental Hygiene and Therapy Members Regarding the Need for Clinical Support by a Dental Nurse

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives In the United Kingdom (UK), Dental Hygienists (DHs) and Dental Therapists (DTs) are required by the UK's regulatory body, the General Dental Council, to “… be appropriately supported when treating patients”. However, what is deemed ‘appropriate support’, and the need for that support, has been ‘open to interpretation’, and ...
Debbie Reed, Laura McClune, Sarah Murray, Frances Robinson, Miranda Steeples   +4 more
wiley   +1 more source

Heat Shock Protein Chaperome Is a Multi-Faceted Vector for Tumor Cell Migratory Activity, Invasion, and Metastasis. [PDF]

Cells
Fedorov V, Kurkin A, Fofanov G, Kaneva V, Kondratenko A, Combs SE, Shevtsov M.   +6 more
europepmc   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

International Journal of Dermatology, EarlyView.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf, Maartje Hendrika Pieternel Rauwenhoff, Michel van Geel, Peter Martin Steijlen, Valerie Lydie Roland Marc Verstraeten   +4 more
wiley   +1 more source

Role of FK506 binding protein 51 in central nervous system diseases. [PDF]

Front Mol Neurosci
Peng H, Wei Y, Qiu Y, Bi R, Zeng L, Hu B, Li Y.   +6 more
europepmc   +1 more source

Midwives' Perception Towards Male Partners' Involvement in Labour Companionship: A Qualitative Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Background Labour companionship is a recommendation by WHO that health authorities enable women to choose a companion during labour to ensure a safe and dignified labour experience for the birthing woman. However, most healthcare facilities in low‐ and middle‐income countries do not necessarily consider this maternal need, which hampers a ...
Tulian Chen, Yajing Wang, Zexuan Xu, Ting Wang, Tingting Fan, Guorong Jiang   +5 more
wiley   +1 more source

Overcoming cancer drug resistance through small-molecule targeting of HSP90 and HSP70. [PDF]

Cancer Drug Resist
Cai RD, Lin MJ, Ye QM.
europepmc   +1 more source