Results 221 to 230 of about 129,105 (287)

ChREBP refines the hepatic response to fructose to protect the liver from injury [PDF]

, 2017
Angela M. Hall, Brian N. Finck, Hetz, Montgomery   +3 more
core   +3 more sources

Targeting cuproptosis for treatment and prognostic assessment in endometrial cancer. [PDF]

Cancer Cell Int
Yu J, Shi H, Zhang J, Shan W, Xu Q, Shang H.   +5 more
europepmc   +1 more source

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

Annals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge, Hongying Sun, Jia Zhang, Yang Yang, Jian Mao, Cheliger   +5 more
wiley   +1 more source

From Protein Folding to Precision Therapy: Surfactant Protein A in the Spotlight. [PDF]

Am J Respir Cell Mol Biol
Ziehr DR, Chivukula RR.
europepmc   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

Protein characterization of the IgM triplet involved in the diagnosis of congenital toxoplasmosis. [PDF]

Parasite
Carreno M, Villard O, Villena I, Peyclit L, Diemer H, Schaeffer-Reiss C, L'Ollivier C.   +6 more
europepmc   +1 more source

A case of cardiac involvement in Fabry disease caused by the p.D313Y variant of the GLA-gene. [PDF]

Eur Heart J Case Rep
Schnieder AL, Zellerhoff S, Bremer C, Özgün MA.   +3 more
europepmc   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Metabolic functions for molecular chaperones and stress proteins in microcephaly. [PDF]

Cell Mol Life Sci
Morris MJ, Ng DCH.
europepmc   +1 more source