Hsp70 and Hsp90 post-translational modifications and translating the chaperone code. [PDF]
Backe SJ, Heritz JA, Mollapour M.
europepmc +1 more source
14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
Targeted proteomics reveal α-MSH-like Enterobacterial ClpB protein in gut microbiota of patients with anorexia nervosa. [PDF]
Bremard L +6 more
europepmc +1 more source
Routine psychosocial care in infertility and medically assisted reproduction - a guide for fertility staff: External Review Report [PDF]
Baor, Liora +13 more
core
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
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Navigating the landscape of protein folding and proteostasis: from molecular chaperones to therapeutic innovations. [PDF]
Kuzu OF, Granerud LJT, Saatcioglu F.
europepmc +1 more source
Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2) [PDF]
et al,, Picus, Joel
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ABSTRACT The vital cofactors NADH and NADPH are prone to hydration, forming hydroxylated redox‐inactive derivatives (NADHX and NADPHX) in cells. These damaged metabolites are repaired by two highly conserved enzymes, an NAD(P)HX dehydratase (NAXD) and an NAD(P)HX epimerase (NAXE).
Myrto Patraskaki +6 more
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