Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury
Cells, 2020 The 70 kDa heat shock protein (HSP70) is a stress-inducible protein that has been shown to protect the brain from various nervous system injuries. It allows cells to withstand potentially lethal insults through its chaperone functions.
Jong Youl Kim +5 more
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Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy [PDF]
, 2019 The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins.
Cappello F. +4 more
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Chaperone use in medical practice
South African Family Practice, 2003 It maybe speculated that having a chaperone present during the intimate clinical examination was originally instituted to protect woman from inappropriate advances by the doctor.
Graham R. Howarth
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Frontiers in Immunology, 2022 In systemic lupus erythematosus, T cells display multiple abnormalities. They are abnormally activated, secrete pro-inflammatory cytokines, help B cells to generate pathogenic autoantibodies, and provoke the accumulation of autoreactive memory T cells ...
Nicolas Schall +6 more
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Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 [PDF]
, 2020 Cancer therapeutics: Extending a drug's reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment.
Chae, Young Chan +10 more
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Chaperoning in GUM clinics [PDF]
Sexually Transmitted Infections, 2004 In the report by the MSSVD on chaperoning in genitourinary medicine (GUM) clinics, it was suggested that patient acceptability with regard to chaperoning needed to be assessed.1 We have recently completed a survey on patients attending our GUM clinic looking at our practice for offering chaperones for intimate examinations.
openaire +1 more source
Melusin promotes a protective signal transduction cascade in stressed hearts.
Frontiers in Molecular Biosciences, 2016 Melusin is a chaperone protein selectively expressed in heart and skeletal muscles. Melusin expression levels correlate with cardiac function in pre-clinical models and in human patients with aortic stenosis.
Mara Brancaccio, Matteo Sorge
doaj +1 more source
Use of chaperones in clinics for genitourinary medicine: survey of consultants [PDF]
BMJ, 1999 Editorial by Bignall In 1996 the United Kingdom's General Medical Council recommended offering chaperones during intimate examinations whenever possible This advice was incorporated into a report from the Royal College of Obstetricians and Gynaecologists.1 Surveys on chaperones have been undertaken in general practice and paediatrics.2–4 Information ...
C J, Torrance, R, Das, M C, Allison
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Chaperone use during intimate examinations in primary care: postal survey of family physicians
BMC Family Practice, 2005 Background Physicians have long been advised to have a third party present during certain parts of a physical examination; however, little is known about the frequency of chaperone use for those specific intimate examinations regularly performed in ...
Upshur Ross EG +2 more
doaj +1 more source
Subinhibitory concentrations of trimethoprim and sulfamethoxazole prevent biofilm formation by Acinetobacter baumannii through inhibition of Csu pilus expression [PDF]
, 2017 Acinetobacter baumannii is emerging as a multidrug-resistant nosocomial pathogen of increasing threat to human health worldwide. Pili are important bacterial virulence factors, playing a role in attachment to host cells and biofilm formation.
Feldman, Mario F +2 more
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