FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Character level attention siamese networks for Chinese handwriting comparison. [PDF]
PLoS OneZhu L, Tang L, Mao H.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Characterization of characters and pseudo-characters
, 2016 Let \(R\) be an algebra over a commutative ring \(A\). An \(A\)-linear functional \(f:R\to A\) is called central if \(f(xy)=f(yx)\) for all \(x,y\in R\). For a central functional \(f\), a map \(S_n(f):R\to A\) is defined by \(S_n(f)(x)=\sum_{\sigma\in{\mathfrak S}_n}\varepsilon(\sigma)(\sigma\cdot f)(x)\), where \({\mathfrak S}_n\) is the symmetric ...
openaire +1 more source
Diradical Character of Cyclic Allenes Enables Their Thermal (2 + 2) Cycloadditions. [PDF]
J Am Chem SocGilbertson NW +4 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Dual-route processing of horizontally and vertically jumbled Chinese words: evidence from ND250 and LAN. [PDF]
Front PsycholHu A, Liu S, Gu F.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Multi-View Occluded License Plate Recognition: A Feature Fusion Method Based on Spatial Wavelet Transform. [PDF]
Sensors (Basel)Pan N, Zhang K, Ghaffar MA, Peng L.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source