Results 141 to 150 of about 2,867,752 (358)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The nature of natural: defining natural character for the New Zealand context

, 2010
New Zealand has a long-standing statutory policy goal to preserve the natural character of the coastal environment and various freshwater environments and their margins. In the absence of an authoritative definition, it has not been possible to develop a
Bornman, Janet, Bornman, Janet F., Froude, Victoria A., Froude, V, Rennie, Hamish, Rennie, Hamish Gordon, Rennie, H., Bornman, J, Froude, V.   +8 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A simple method for displaying the hydropathic character of a protein.

Journal of Molecular Biology, 1982
J. Kyte, R. Doolittle
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Penyuluhan perilaku hidup bersih dan sehat (PHBS) melalui cuci tangan pakai sabun (CTPS) kepada siswa SDN Panunggangan 4 sebagai upaya menanamkan nilai bela negara

Abdimas Altruis
Clean handwashing practices are one of the fundamental factors of Clean and Healthy Living Behavior (PHBS), making it essential to instill this habit from an early age.
Audrey Gondokusumo Widjaja, Nicholas, Timotius Enrico Valentino, Ferdy Anthonius, Christian Siregar   +4 more
doaj   +1 more source

Virtue and argument: Taking character into account

, 2013
In this paper we consider the prospects for an account of good argument that takes the character of the arguer into consideration. We conclude that although there is much to be gained by identifying the virtues of the good arguer and by considering the ...
Justine Kingsbury, Kingsbury, Justine, Tracy Bowell, Bowell, Tracy   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Solving Problems In Mathematics Using The Personality Types As A Means Of Developing The Nation’s Character

, 2011
HARDIKNAS’(The National Education Day) 2011 is ‘ Indonesia resurgent and having the special character’. By developing the nation character, we hope it can create the superior Indonesian people.
M.J. Dewiyani , S
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source