Results 211 to 220 of about 4,920,840 (345)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

CharMark: character-level Markov modeling for interpretable linguistic biomarkers of cognitive decline. [PDF]

Front Digit Health
Mekulu K, Aqlan F, Yang H.
europepmc   +1 more source

Effects of Sweet Potato and Green Tea Waste Used as Feed on the Performance and Blood Character of Meishan Pigs during Fattening Period

, 2013
Miki MINO, Seizi Sukemori, Shuhei Ikeda
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Modular synthesis of benzothiophene-fused pentalenes reveals substituent-dependent antiaromaticity. [PDF]

Chem Sci
Isogai R, Yasui K, Fukazawa A.
europepmc   +1 more source

The Language Character of Midu Folk Song

, 2020
Yukun Chen
openalex   +2 more sources

Green Fruit Characters of Cucumber as Related to Quality Factors in Brine Stock1 [PDF]

, 1970
F. D. Sneed, J. L. Bowers
openalex   +1 more source

Acquired Characters [PDF]

Nature, 1894
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Elastic Energy Storage in Al-Al₄C₃ Composites: Effects of Dislocation Character and Interfacial Graphite Formation. [PDF]

Materials (Basel)
Santos Beltrán A, Gallegos Orozco V, Medrano Prieto HM, Estrada Guel I, Reyes CGG, Santos Beltrán M, Santos Gallegos DV, Gallegos Orozco C, Martínez Sánchez R.   +8 more
europepmc   +1 more source