Results 71 to 80 of about 1,736,810 (289)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

SOFT SKILL DAN CHARACTER BUILDING MAHASISWA

Tadris: Jurnal Pendidikan Islam, 2009
There are three aspects concerning the development of students, they are cognitive, affective, and psychomotoric aspects. Soft skill is unseperated aspect of affective one.
H a r y u -
doaj   +3 more sources

Mathematics Learning Within Culture And Nation Character: Using Traditional Dance In Learning The Concept Of Symmetry At Grade IV Primary School [PDF]

, 2011
This paper introduces a new approach in mathematics learning within culture and nation character. Indonesian traditional dances are used as a context in learning the concept of symmetry.
Yullys , Helsa, Yusuf , Hartono
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Building Character

Colloquia, Academic Journal of Culture and Thought, 2019
This project is an attempt to design a method of teaching English as a foreign language to Ecuadorian university students by applying Gee's theory of "situated learning”. The researcher posed the following problem: How can global empathy be incorporated into the EFL classroom so as to increase students’ intrinsic motivation to learn
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

To Build a Notion:US State Department Nation Building Expertise and Postwar Settlements in 20th Century East Central Europe [PDF]

, 2013
This article offers a contribution to the sociology of social science knowledge practices and expertise through the empirical lens of US nation building policies.
Abela A., Adcock R., Amadae S. M., Bass G. J., Chollet D., Clubb J. M., Daalder I., Daalder Ivo, Fink C, Gelfand L., Gilman N., Glazer N., Grose P., Hall J. A., Hofstadter R., Ignatieff M., King D., Klug H., Koh H. H., Kuklick B., Lansing R., Light J., Mallard G., Mannheim K., Mcgerr M., Medvetz T., Medvetz T., Ngai M., Nicholson H., Nystuen G., O'brien J., O'sullivan C. D., Perlmann J., Ross D., Scheffer D., Schulten S., Seymour C., Seymour C., Shattuck J., Shklar J., Skocpol T., Smith J. A., Weber M., Zeidel R., Zolberg A.   +44 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source