Results 111 to 120 of about 1,696,735 (353)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Embodying character education values: "Malin Kundang" and community character development

open access: yesJournal of Community Service and Empowerment
Intangible heritage, such as folklore, plays a crucial role in preserving cultural values and traditions. Regular efforts are needed to ensure these stories, and their embedded values are passed down through generations.
F. Ferdinal, O. Oktavianus
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

The Education of the National Character of Pancasila in Secondary School Based on Pesantren [PDF]

open access: yes, 2017
This study is aimed at describing (1) Pancasila-based character education in pesantren-based secondary schools, (2) the strategy employed by teachers in developing Pancasila-based character education, and (3) the obstacles faced by teachers in developing
Kuncorowati, P. W. (Puji)   +2 more
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

The VIA Inventory of Strengths, Positive Youth Development, and Moral Education [PDF]

open access: yes, 1935
The VIA Inventory of Strengths and the VIA model were originally developed to assess and study 24 character strengths. In this paper, I discuss how the VIA Inventory and its character strength model can be applied to the field of moral education with ...
Han, Hyemin
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Pendidikan Karakter Perspektif Al-Qur’an

open access: yesINSANIA: Jurnal Pemikiran Alternatif Kependidikan, 2013
: Character education is now indeed become a major issue of education in Indonesia today. In addition to being part of the process of formation of the child character, character education is also expected to become a major foundation in the form of ...
Slamet Yahya
doaj  

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