Results 71 to 80 of about 8,760,090 (255)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
One of the objectives of national education is to prepare character education activities in the form of forming character and character for the next generation of the nation.
Tiara Osa Meutia +2 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Strengthening of early children's character education stunting children in Indonesia. [PDF]
Arifuddin A +9 more
europepmc +1 more source
Report From the Social and Character Development Research Program [PDF]
Report evaluating seven Social and Character Development (SACD) programs designed to positively impact behavior and academic performance of a cohort of elementary students during their third through fifth grade years (2004-2007).
Allen, Ruby, Doolittle, Emily
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Character education and virtues
The subject of character education has aroused increasing interest over the past decades, during which several specialised research centres have taken shape.
Andrea Porcarelli
doaj +1 more source
The Importance of Character Education for Tweens as Consumers [PDF]
Tweens is a term that denotes a market segment mentality that falls between children at the lower end and teens at the upper end. Tweens marketing strategies are considered critical for most global brands.
Ahmed Taher +2 more
core

