Results 101 to 110 of about 1,400,025 (294)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The role of character positional frequency on Chinese word learning during natural reading.

open access: yesPLoS ONE, 2017
Readers' eye movements were recorded to examine the role of character positional frequency on Chinese lexical acquisition during reading and its possible modulation by word spacing.
Feifei Liang   +6 more
doaj   +1 more source

Leader's guide to building collaboration

open access: yes, 2005
Title from cover; at head of title: Change our world.; Pages 30-32 lined, for making notes.; Includes bibliographical references (p.

core  

Stopping region-based image segmentation at meaningful partitions [PDF]

open access: yes, 2007
This paper proposes a new stopping criterion for automatic image segmentation based on region merging. The criterion is dependent on image content itself and when combined with the recently proposed approaches to syntactic segmentation can produce ...
O'Connor, Noel E.   +4 more
core   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

KWH METER IMAGE ENHANCEMENT USING COLOR SPACE TRANSFORMATION FOR IMPROVING CHARACTER SEGMENTATION ACCURACY

open access: yesJurnal Ilmiah Kursor: Menuju Solusi Teknologi Informasi, 2016
This study proposes an approach to enhance image quality of power meter (KWH meter) using a color space transformation. Power meter is used to measure the power consumption of the customer.
Shinta Puspasari, Lastri Widya Astuti
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Distance Regularized Level Set Evolution for Medical Image Segmentation [PDF]

open access: yes, 2013
Medical image is an important tool because it can be used for surgical planning and simulation, radiotherapy planning, and tracking the progress of disease. To analyze the medical image, it must partitioned into different segment using image segmentation
Pranowo, Pranowo, Rianto , Indra
core   +1 more source

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