Results 81 to 90 of about 86,808 (266)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Root characteristics in salt tolerance.
The mechanisms of salt tolerance in plants were reviewed focusing on root characteristics of salt-tolerant cultivars under saline conditions. The salt-tolerant traits were characterized as greater root growth, higher efficiency in water uptake, lower Na+ permeability, better root osmotic adjustment, and higher root pressure.
An, Ping +4 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A matrix with real characteristic roots
In this note we prove the conjecture of J. D. Hoffman and B . M. Axilrod that a matrix with these properties has only real cha,racteristic roots and that these characteristic roots lie between zero and twice the maximum diagonal element. The second statement is a direct consequence of the first and properties (1), (2), and (3) by the theorem of S ...
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The characteristic galls or knots on the roots of trees and vines which are caused by root-knot nematodes make this pest easy to recognize in the field.
M Allen
doaj
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
We consider the linear differential equation $$ sum_{k=0}^n a_k(t)x^{(n-k)}(t)=0quad tgeq 0, ; ngeq 2, $$ where $a_0(t)equiv 1$, $a_k(t)$ are continuous bounded functions.
Michael I. Gil
doaj

