Results 41 to 50 of about 2,364,233 (302)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A characteristic energy scale in glasses

open access: yes, 2018
Glasses feature a broad distribution of relaxation times and activation energies without an obvious characteristic scale. At the same time, macroscopic quantities such as Newtonian viscosity and nonlinear plastic deformation, are interpreted in terms of ...
Bouchbinder, Eran, Lerner, Edan
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The influence of silicification on coal low-temperature oxidation characteristic parameters

open access: yesMeikuang Anquan, 2022
In order to study the effect of silicification on low temperature oxidation characteristics of coal, scanning electron microscopy(SEM) was used to observe the difference of pore structure between silicified coal and non-silicified coal; the temperature ...
JIN Yongfei, ZHANG Guang, GUO Jun, LIU Yin, YAN Hao
doaj   +1 more source

Nonequilibrium Microscopic Distribution of Thermal Current in Particle Systems

open access: yes, 2009
A nonequilibrium distribution function of microscopic thermal current is studied by a direct numerical simulation in a thermal conducting steady state of particle systems.
Abramowitz M.   +14 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Experimental Study on the Thermal Behavior Characteristics of the Oxidative Spontaneous Combustion Process of Fischer–Tropsch Wax Residue

open access: yesFire
Coal-to-liquid technology is a key technology to ensuring national energy security, with the Fischer–Tropsch synthesis process at its core. However, in actual production, Fischer–Tropsch wax residue exhibits the characteristics of spontaneous combustion ...
Tongshuang Liu   +6 more
doaj   +1 more source

Fluctuation corrections on thermodynamic functions: Finite size effect

open access: yes, 2013
The explicit thermodynamic functions, in particular, the specific heat of a spin system interacting with a spin bath which exerts finite dissipation on the system are determined.
Ghosh, Arnab   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experimental study on the inhibition of spontaneous combustion characteristics of coal by magnesium salt inhibitor

open access: yesMeikuang Anquan
In order to study the effect of magnesium salt (magnesium chloride hexahydrate + magnesium hydroxide) on the retarding characteristics of coal spontaneous combustion, the effects of inhibitor dosage and silane coupling agent on the characteristic ...
Zimeng CHENG   +5 more
doaj   +1 more source

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