Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The breed influence in pork quality and intramuscular fatty acid comp composition
The aim of this research was to investigate whether meat quality and intramuscular fatty acid composition are affected by breed in pigs. The samples of pork for analysis were taken from Yorkshire (Y), Pietrain (P) Lithuanian White (LW), Lithuanian Large
EDITA MESHKINYTE-KAUSHILI +5 more
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Emerging adulthood features and criteria for adulthood: Variable- and person-centered approaches [PDF]
Reaching adulthood is the aim of the transition to adulthood; however, emerging adults differently define both adulthood and the transitional period they are living. Variable-centered and person-centered approaches were integrated in the present paper to
Leerstoel Branje +4 more
core +2 more sources
Scattering Characteristics of Targets above a Rough Surface in SAR Images
The modeling, simulation, and analysis of target characteristics are essential to a synthetic aperture radar (SAR) image-based autotarget recognition (ATR) system.
Bo Zhao, Tie Jun Cui
doaj +1 more source
Mechanistic insights into nitric acid-enhanced iodic acid particle nucleation in the upper troposphere and lower stratosphere [PDF]
In the upper troposphere and lower stratosphere (UTLS), new particles frequently form to seed cloud condensation nuclei (CCN), thereby affecting radiative forcing and global climate.
J. Li +9 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
CEO Characteristics and Audit Report Lag: Evidence from Egypt [PDF]
PurposeThis study aims to investigate the relationship between Chief Executive Officer (CEO) characteristics and audit report lag (ARL) in Egypt, an emerging economy characterized by high power distance and a culture of secrecy.
Elsayed Ibrahim, Awad +3 more
core +1 more source
Neurobiological stress responses predict aggression in boys with oppositional defiant disorder/conduct disorder: a 1-year follow-up intervention study [PDF]
To improve outcome for children with antisocial and aggressive behavior, it is important to know which individual characteristics contribute to reductions in problem behavior.
van Goozen, Stephanie H M +17 more
core +3 more sources

