Results 121 to 130 of about 12,335,782 (303)
Scientific ReportsPanax japonicus C. A. Mey. is a rare and endangered Class II important protected wild medicinal plant in China with a wide range of pharmacological activities.
Xi Lun Huang +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
PREDICTING COUPON USE FROM SHOPPER DEMOGRAPHIC AND BEHAVIORAL CHARACTERISTICS [PDF]
We surveyed of grocery shoppers in the Northeast United States to measure how demographic characteristics and consumer behavior affect the use of four coupon types (paper, in-store, checkout, and online).
Park, Kristen, Gomez, Miguel I.
core
Characteristics of Urban Heat Island in Enugu during Rainy Season [PDF]
, 2012 Aim The rainy season UHI characteristics at several sites in Enugu urban were evaluated using paired measurement programme The aim was to determine the characteristic of urban heat island in the city during rainy season periods Study Design Survey ...
Dr. Enete
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Are Intervention-Design Characteristics More Predictive than Baseline Participant Characteristics on Participant Attendance to a Paediatric, Community Weight Management Programme? [PDF]
, 2015 BACKGROUND: Approximately 50% of participants complete a paediatric weight management programme, yet the predictors of attendance and dropout are inconsistent.
Pringle, Andy +4 more
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source