Results 211 to 220 of about 18,304,067 (333)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

The Development of Rumen Function in the Dairy Calf I. Some Characteristics of the Rumen Contents of Cattle of Various Ages

, 1955
F.W. Lengemann, N. N. Allen
openalex   +1 more source

Some uniform characteristics of the primate auricle [PDF]

, 1922
George L. Streeter
openalex   +1 more source

Indirect role of climatic suitability in mediating the effects of plant characteristics on naturalization success of cultivated alien plants in Southern Africa. [PDF]

Biol Invasions
Peter SO, Essl F, Lenzner B, van Kleunen M, Omer A.   +4 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

A method for obtaining the characteristic equation of a matrix and computing the associated modal columns [PDF]

, 1950
Henry E. Fettis
openalex   +1 more source

The correlation analysis between preoperative cerebral small vessel disease and carotid plaque echo characteristics. [PDF]

Front Neurol
Zhou Y, Yan P, Guo S, Huang Y, Jiang L.
europepmc   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Characteristics of the circulation of hypersensitive rabbits

, 1941
Gregory M. Brown, B. G. Maegraith
openalex   +2 more sources

ON THE INHERITANCE OF BODY FORM AND OF CERTAIN OTHER CHARACTERISTICS, IN THE CONJUGATION OF EUPLOTES PATELLA [PDF]

, 1934
Bernard M. Cohen
openalex   +1 more source