Results 141 to 150 of about 10,370,537 (363)

Micromechanical testing for quantitative characterization of apparent slip system: Extinction of persistence of slip in carbon bearing Fe-3% Si

, 2023
Masaki Tanaka, M Takenaka, Shigeto Yamasaki, Tatsuya Morikawa   +3 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

On the Evaluation of the Hyperthermic Efficiency of Magnetic Scaffolds

IEEE Open Journal of Engineering in Medicine and Biology
Goal: Deep-seated tumors (DST) can be treated using thermoseeds exposed to a radiofrequency magnetic field for performing local interstitial hyperthermia treatment (HT).
Matteo B. Lodi, Antonios Makridis, Konstantina Kazeli, Theodoros Samaras, Makis Angelakeris, Giuseppe Mazzarella, Alessandro Fanti   +6 more
doaj   +1 more source

Next-generation characterization of the Cancer Cell Line Encyclopedia

Nature, 2019
M. Ghandi, F. Huang, Judit Jané-Valbuena, G. Kryukov, Christopher C. Lo, E. McDonald, J. Barretina, Ellen T. Gelfand, C. Bielski, Haoxin Li, K. Hu, Alexander Y. Andreev-Drakhlin, Jaegil Kim, J. Hess, B. Haas, F. Aguet, B. Weir, M. Rothberg, B. Paolella, M. Lawrence, Rehan Akbani, Yiling Lu, Hong L. Tiv, P. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, J. Shih, Kevin Hadi, Yanay Rosen, J. Bistline, K. Venkatesan, Anupama Reddy, D. Sonkin, Manway Liu, J. Lehár, Joshua M. Korn, D. Porter, Michael D. Jones, J. Golji, G. Caponigro, Jordan E. Taylor, C. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, A. Kauffmann, Nicolas Stransky, M. Imieliński, Y. Maruvka, A. Cherniack, Aviad Tsherniak, F. Vazquez, Jacob D. Jaffe, A. Lane, D. Weinstock, Cory M. Johannessen, Michael P. Morrissey, F. Stegmeier, R. Schlegel, W. Hahn, G. Getz, G. Mills, J. Boehm, T. Golub, L. Garraway, W. Sellers   +67 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Characterization of microRNA transcriptome in lung cancer by next‐generation deep sequencing

, 2014
Jie Ma, Kaiissar Mannoor, Lu Gao, Afang Tan, Maria Guarnera, Min Zhan, Amol C. Shetty, Sanford A. Stass, Lingxiao Xing, Feng Jiang   +9 more
openalex   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Novel polymer thin film fabrication for graphitization studied by in situ transmission electron microscopy [PDF]

BIO Web of Conferences
Chemin Chloé, Rezaei Babak, Fanta Alice Bastos da Silva, Bunea Ada-Ioana, Keller Stephan Sylvest, Hansen Thomas Willum   +5 more
doaj   +1 more source