Results 81 to 90 of about 3,440,878 (318)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Ultrafast Photocatalytic Wettability Switching in Substrate‐Interface Tailored Titanium Dioxide Thin Films

open access: yesAdvanced Materials Interfaces
In this study, we investigate the ultrafast photocatalytic wettability switching in titanium dioxide (TiO2) thin films, tailored at the substrate‐interface level. We explore the effects of silicon substrate doping and the introduction of interface oxides
Rucha A. Deshpande   +6 more
doaj   +1 more source

SEISMIC ATTRIBUTES ASSISTED QUANTITATIVE UNCONVENTIONAL RESERVOIRS CHARACTERIZATION [PDF]

open access: yes, 2018
Unconventional reservoirs cover a wide range of hydrocarbon-bearing formations and reservoir types that generally do not produce economic rates of hydrocarbons without stimulation.
Qi, Xuan
core  

Suppression effect of Ni grain size on the Ni3Sn4 growth at the Sn/Ni interface

open access: yes, 2017
Effect of Ni grain size on the formation and growth kinetics of intermetallic compounds at the Sn/Ni interface is studied. For a coarse-grained Ni foil, only the Ni3Sn4 phase is formed with a thickness of 28 μm after aging at 200 °C for 1000 h.
Hsuan Lee   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans

open access: yes, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L   +26 more
core   +1 more source

Pore- and micro-structural characterization of a novel structural binder based on iron carbonation [PDF]

open access: yes, 2014
: The pore- and micro-structural features of a novel binding material based on the carbonation of waste metallic iron powder are reported in this paper.

core   +1 more source

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