Results 121 to 130 of about 41,376 (286)
ABSTRACT Background and Purpose Spinal and bulbar muscular atrophy (SBMA) is an adult‐onset X‐linked neuromuscular disorder associated with progressive weakness, sensory involvement and impaired mobility. Falls appear frequent in SBMA, but their real‐world frequency and circumstances have not been systematically described.
Laurence E. Lee +5 more
wiley +1 more source
ABSTRACT Background Parent carers of children with neurodisability are empowered when they have greater agency and influence over decisions about their child's care. When parent carers are empowered, it benefits both them and their children. Building on previous work, this study aimed to co‐produce a Theory of Change (ToC) to inform the development of ...
Jim Reeder +5 more
wiley +1 more source
Cerveau / Charcot, Jean Martin
Manuscrit, 417 feuillets (Fonds Charcot : Manuscrits des leçons de J.M.Charcot.
Charcot, Jean Martin
core
Leçons de 1873 / Charcot, Jean Martin
Leçons, 699 feuillets (Fonds Charcot : Manuscrits des leçons de J.M.Charcot.
Charcot, Jean Martin
core
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai +9 more
wiley +1 more source
Goutte Rhumatisme / Charcot, Jean Martin
Manuscrit, 137 feuillets (Fonds Charcot : Manuscrits des leçons de J.M.Charcot.
Charcot, Jean Martin
core
Leçons de 1872 / Charcot, Jean Martin
Leçons, 474 feuillets (Fonds Charcot : Manuscrits des leçons de J.M.Charcot.
Charcot, Jean Martin
core
Changes in serum β‐synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Alba Cervantes González +23 more
wiley +1 more source
Poumons. Pneumonie / Charcot, Jean Martin
Manuscrit, (Fonds Charcot : Manuscrits des leçons de J.M.Charcot.
Charcot, Jean Martin
core

