Results 71 to 80 of about 78,454 (292)
Arthroplasty of a Charcot knee
Orthopedic Reviews, 2010 The Charcot knee - or neuropathic arthropathy - presents a considerable challenge to the orthopaedic surgeon. Caused by a combination of sensory, motor and autonomic neuropathy, it was originally described as an arthritic sequelae of neurosyphilis.
Sina Babazadeh +3 more
doaj +1 more source
Trends in Utilization of Charcot Reconstruction
Foot & Ankle Orthopaedics, 2023 Category: Ankle; Diabetes Introduction/Purpose: Charcot arthropathy of the foot and ankle is a challenging complication of peripheral neuropathy with a 0.1% and 5.0% incidence in the diabetic population.
William Newton BS +4 more
doaj +1 more source
Foot & Ankle Surgery: Techniques, Reports & Cases, 2021 Ankle Charcot deformity can occur after midfoot Charcot reconstruction, especially when patients present with hindfoot varus or pre-existing ankle instability.
Nicole K. Cates, DPM, AACFAS +2 more
doaj +1 more source
An Inversion Disrupting FAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed [PDF]
, 2016 Sensory neuropathy in the Border Collie is a severe neurological disorder caused by the degeneration of sensory and, to a lesser extent, motor nerve cells with clinical signs starting between 2 and 7 months of age.
Beltran, E +9 more
core +4 more sources
Expansion of invasive carabids across elevation and habitats on sub‐Antarctic South Georgia
Insect Conservation and Diversity, EarlyView.Two introduced carabid species have continued to expand their ranges on the sub‐Antarctic island of South Georgia over the past 10–15 years. The species have colonised inland valleys and are present across habitats but are more abundant in those with high vegetation cover. N‐mixture models revealed the optimal sampling method, intensity and habitat for
Pierre Tichit +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Charcot’s famous secretaries [PDF]
Arquivos de Neuro-Psiquiatria, 2017 ABSTRACT At the pinnacle of his career, Professor Charcot had four secretaries: Charles Féré, Pierre Marie, Georges Gilles de la Tourette and Georges Guinon. They helped the great founder of neurology with his activities at La Salpêtrière Hospital and his private clinic, examining patients before he made the final diagnosis.
Teive, Hélio Afonso Ghizoni +3 more
openaire +5 more sources
Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. [PDF]
, 2017 SCL25A46 is a mitochondrial carrier protein that surprisingly localizes to the outer membrane and is distantly related to Ugo1. Here we show that a subset of SLC25A46 interacts with mitochondrial dynamics components and the MICOS complex.
Claypool, Steven M +6 more
core +1 more source
Variant Prioritization by Pedigree‐Based Haplotyping
Genetic Epidemiology, Volume 50, Issue 3, April 2026.ABSTRACT Whole genome sequence (WGS) data provides opportunities for comprehensive evaluation of variants that may influence complex traits. However, prioritizing the large number of variants, particularly those in non‐coding regions, is a challenge.
Rafael A. Nafikov +8 more
wiley +1 more source
From the cell membrane to the nucleus: unearthing transport mechanisms for Dynein [PDF]
, 2012 Mutations in the motor protein cytoplasmic dynein have been found to cause Charcot-Marie-Tooth disease, spinal muscular atrophy, and severe intellectual disabilities in humans. In mouse models, neurodegeneration is observed.
A. Friedman +53 more
core +1 more source