Results 111 to 120 of about 8,815,514 (254)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Modeling charge collection in x-ray imagers

, 2017
We present a TCAD simulation-based investigation of charge transport and charge collection mechanisms of a pinned photodiode pixel for X-ray imaging. Following static simulations to determine the electric-field and potential profiles, charge collection ...
SELMI, Luca, PILOTTO, ALESSANDRO, Pierpaolo Palestri, Alessandro Pilotto, PINAROLI, GIOVANNI, PALESTRI, Pierpaolo, Luca Selmi, Giovanni Pinaroli   +7 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Position-resolved charge collection of silicon carbide detectors with an epitaxially-grown graphene layer

Scientific Reports
Silicon carbide (SiC) has outstanding physical properties therefore, diodes based on SiC are being considered for many radiation detection applications such as particle accelerator experiments and medical dosimetry. Moreover, by reducing the metal on the
Ivan Lopez Paz, Philippe Godignon, Neil Moffat, Giulio Pellegrini, Joan Marc Rafí, Gemma Rius   +5 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Mobility‐Lifetime Products in Organic Infrared Photodiodes with Peak Absorption at 1550 nm

Advanced Electronic Materials
Infrared photodiodes based on organic semiconductors are promising for low‐cost sensors that operate at room temperature. However, their realization remains hampered by poor device efficiency.
Bogyeom Seo, Tyler Bills, Paramasivam Mahalingavelar, Woojo Kim, Hyeong Ju Eun, Jong H. Kim, Jason D. Azoulay, Tse Nga Ng   +7 more
doaj   +1 more source

Charge collection measurements in single-type column 3D sensors

, 2007
We report on charge collection studies on 3D silicon detectors of single-type column n-diffusions in p-substrate, configured either as strip or as pad detectors.
Piemonte, Claudio, Ronchin, Sabina, Hartmut F. W. Sadrozinski, Boscardin, Maurizio, Zorzi, Nicola, Carlo Tosi, Dalla Betta, Gian Franco, Monica Scaringella, Mara Bruzzi, Aleksandr Polyakov, Pozza, Alberto   +10 more
core   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham, Casey Vanderlip, Colin Birkenbihl, Eashwar Krishna, Chizobam Ugboaja, Andrew E. Budson, Brandon Frank, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

Molecular Diagnosis in Children With Febrile Seizures: Beyond the Conventional Clinical Classification

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Febrile seizures (FS) are currently classified as simple or complex primarily to describe seizure characteristics, with limited ability to identify the underlying etiology. We evaluated whether molecular diagnosis could complement conventional classification and improve the diagnosis and management of FS.
Jia Wang, Mengna Zhang, Yangyang Wang, Xiuyu Shi, Baoguang Li, Xiuxia Wang, Dan Sun, Sanqing Xu, Jianbo Zhao, Lijun Du, Qiming Pang, Xiaoming Liu, Chunhui Tang, Xiaohua Li, Jiuwei Li, Yanli Ma, Jianxiang Liao, Gulixian Abudureyimu, Jianmin Liang, Yuan Wang, De Wu, Jian Wu, Liping Zou   +22 more
wiley   +1 more source

Time resolved ion beam induced charge collection

, 2000
Under this effort, a new method for studying the single event upset (SEU) in microelectronics has been developed and demonstrated. Called TRIBICC, for Time Resolved Ion Beam Induced Charge Collection, this technique measures the transient charge ...
Sexton, Frederick W., Walsh, David S., Doyle, Barney L., Dodd, Paul E.   +3 more
core   +1 more source