Results 91 to 100 of about 483,253 (311)

NRS-18217 | Indexes to Charge Books [Tamworth Police Station] [PDF]

open access: yes
<p>Since 1862 there has been an obligation to create Charge books. “The Sergeant, senior Constable, or Constable on duty at the watchhouse received all charges against prisoners brought in by different Constables, ascertained their nature and

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Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

NRS-18218 | Index to Charge Books [Wingham Police Station] [PDF]

open access: yes
<p>Since 1862 there has been an obligation to create Charge books. “The Sergeant, senior Constable, or Constable on duty at the watchhouse received all charges against prisoners brought in by different Constables, ascertained their nature and

core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

NRS-23851 | Charge books [Ulmarra Police Station] [PDF]

open access: yes
<p>Police Rules of 1862 introduced the obligation to keep Charge books to record charges against prisoners, the nature of the charges, the names of those charged as well as any prisoner's property.

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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Unsupervised vector-based classification of single-molecule charge transport data

open access: yesNature Communications, 2016
The stochastic nature of single-molecule charge transport measurements requires collection of large data sets to capture their full complexity. Here, the authors adopt strategies from machine learning for the unsupervised classification of single ...
Mario Lemmer   +4 more
doaj   +1 more source

NRS-23839 | Charge books [Garah Police Station] [PDF]

open access: yes
<p>Police Rules of 1862 introduced the obligation to keep Charge books to record charges against prisoners, the nature of the charges, the names of those charged as well as any prisoner's property.

core  

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