Results 81 to 90 of about 483,253 (311)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Data in Brief, 2019 The authors have recently reported silver nanowire based Cu(In,Ga)Se2 solar cells [1,2]. Metal mesh based transparent electrodes other than the silver nanowire can be also employed or have a potential to provide a better performance for the solar cells ...
Sangyeob Lee +5 more
doaj +1 more source
NRS-16469 | Record of occurrences [Sydney Police Station Charge Room] [PDF]
<p>This series consists of Records of occurrences from the Sydney Police Station Charge Room.</p><p>Records of occurrences are police station diaries providing a detailed record of all occurrences in the area coming to the attention of ...
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
How solar cell efficiency is governed by the αμτ product
Physical Review Research, 2020 The interplay of light absorption, charge-carrier transport, and charge-carrier recombination determines the performance of a photovoltaic absorber material.
Pascal Kaienburg +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
NRS-16953 | Charge books [Balranald Police Station] [PDF]
<p>Since 1862 there has been an obligation to create Charge books. 'The Sergeant, senior Constable, or Constable on duty at the watchhouse received all charges against prisoners brought in by different Constables, ascertained their nature and if ...
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Geard-Ring and Charge Collection Efficiency of GaAs Detector
Advances in Electrical and Electronic Engineering, 2005 The study present the results of an experimental investigation focused on the inflence of guard-ring on detector charge collection. The tested detector is based on semi-insulating (SI) GaAs substrate with a base thinkness of 250 um, where the depletion ...
Andrea Perdochova +3 more
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