Results 41 to 50 of about 484,963 (259)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
For the room temperature nuclear detector application, signal created in the detector depends not only to the energy of the incident photon but also to the position of the interaction.
Cedric E. Beogo +3 more
doaj +1 more source
We investigated the effect of metallization and spatial homogeneity on the charge collection of sensors prepared from high purity semi-insulating 4H-SiC bulk wafer. We used Au, Ni, Cr or graphene electrical contacts subsequently prepared on the same chip.
P. Praus +6 more
doaj +1 more source
Collective space-charge phenomena in the source region [PDF]
Abstract For many devices space-charge-dominated behavior, including the excitation of space-charge collective modes, can occur in the source region, even when the downstream characteristics are not space-charge-dominated. Furthermore, these modes can remain undamped for many focusing periods. Traditional studies of the source region in particle beam
Haber, I. +9 more
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Colloidal quantum dots (QDs) are of great interest in optoelectronic and photovoltaic devices with low-cost processing, strong light absorption, and size tunable direct band gap.
Wenjun Chen +3 more
doaj +1 more source
In Situ Collection of Nanoparticles during Femtosecond Laser Machining in Air
Nanoparticles generated during laser material processing are often seen as annoying side products, yet they might find useful application upon proper collection.
Nithin Joy, Anne-Marie Kietzig
doaj +1 more source
Collective charging of an organic quantum battery
We study the collective charging of a quantum battery (QB) consisting of a one-dimensional molecular aggregate and a coupled single-mode cavity, to which we refer as an ``organic quantum battery" since the battery part is an organic material. The organic QB can be viewed as an extension of the so-called Dicke QB [D. Ferraro \emph{et al}., Phys.
Jiawei Li, Ning Wu
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

