Results 91 to 100 of about 3,914,143 (293)
Threonine 348 regulates the subcellular localization of PTEN
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Qweak: First Direct Measurement of the Proton’s Weak Charge
The Qweak experiment, which took data at Jefferson Lab in the period 2010 - 2012, will precisely determine the weak charge of the proton by measuring the parity-violating asymmetry in elastic e-p scattering at 1.1 GeV using a longitudinally polarized ...
Androic D. +100 more
doaj +1 more source
The investigation of novel electronic phases in low-dimensional quantum materials demands for the concurrent development of new measurement techniques that combine surface sensitivity with high spatial resolution and high measurement accuracy. We propose
Berthold Jäck
doaj +1 more source
The photo charge of a bacterioRhodopsin electrochemical cells measured by a charge amplifier
We propose that electrochemical cells based on bacterioRhodopsin (bR), a photosensitive protein, generate electric charges under illuminated light and that a suitable signal detection apparatus for this cell type is a charge amplifier. By using charge amplifiers, we observed bR-photocell electric charges that were proportional to the intensity of ...
Seiichi Takamatsu +4 more
openaire +2 more sources
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
MEASUREMENT OF CHARGE INSTABILITY OF TIR STRUCTURE
Background. The information content of the complex for measuring the parameters of the TIR structure can be increased by using a GLIN implemented on the basis of a microcontroller in its configuration. Materials and methods.
D.A. Tashlintsev, V.M. Tchaikovsky
doaj +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Measurement-only topological quantum computation without forced measurements
We investigate the measurement-only topological quantum computation (MOTQC) approach proposed by Bonderson et al (2008 Phys. Rev. Lett. http://dx.doi.org/10.1103/PhysRevLett.101.010501 101 http://dx.doi.org/10.1103/PhysRevLett.101.010501 ) where the ...
Huaixiu Zheng, Arpit Dua, Liang Jiang
doaj +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source

