Results 71 to 80 of about 3,914,143 (293)

Highly Sensitive Charge Sensor Based on Atom-Assisted High-Order Sideband Generation in a Hybrid Optomechanical System

open access: yesSensors, 2018
Realizing highly sensitive charge sensors is of fundamental importance in physics, and may find applications in metrology, electronic tunnel imaging, and engineering technology.
Zeng-Xing Liu, Hao Xiong
doaj   +1 more source

Measuring the charged particle multiplicity with ALICE [PDF]

open access: yesIndian Journal of Physics, 2011
The charged particle multiplicity distribution is one of the first measurements that ALICE will be able to perform. The knowledge of this basic property at a new energy is needed to configure Monte Carlo generators correctly with the aim of understanding the background of other, especially rare, processes including new physics.
BARBERA, Roberto   +1 more
openaire   +3 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Development of a novel signal restoration algorithm to eliminate the distorted components in space charge measurement excited by femtosecond laser irradiation

open access: yesHigh Voltage
For the space charge measurement method with optical excitation for electrical insulation, the distortion of the excitation laser on the measurement signal and the accumulation of space charge have not been discussed before.
Tianrun Qi   +6 more
doaj   +1 more source

Design of bunch length and charge monitor based on cavity resonator for injector of Super Tau-Charm Facility

open access: yesHe jishu
BackgroundThe Super Tau Charm Facility (STCF) is a new generation electron-positron colliders at the forefront of high precision, and its high brightness requirements pose a major challenge to accelerator technology.
LYU Tao, WANG Qian, LUO Qing
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

New Discrete Fibonacci Charge Pump Design, Evaluation and Measurement

open access: yesMeasurement Science Review, 2017
This paper focuses on the practical aspects of the realisation of Dickson and Fibonacci charge pumps. Standard Dickson charge pump circuit solution and new Fibonacci charge pump implementation are compared.
Matoušek David   +2 more
doaj   +1 more source

On Measuring the Topological Charge of Anyons

open access: yesProblems of Information Transmission
In this paper we discuss the principles of measuring topological charge or representation traveling in the set of anyons. We describe the procedure and analyze how it works for the different values of parameters of the theory. We also show how it can be modified to be more effective for different levels of Chern-Simons theory.
openaire   +3 more sources

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