Results 21 to 30 of about 101,438 (284)
, 2004 Ultra-sensitive detectors and readout devices based on the radio frequency single electron transistor (rf-SET) combine near quantum-limited sensitivity with fast operation.
A. R. Hamilton +8 more
core +1 more source
Low Noise Charge Sensitive Amplifier with Low Input Impedance [PDF]
IEEE Transactions on Nuclear Science, 1981 This amplifier was designed for use in a large array of proportional wire chambers with charge division readout and for cathode readout of proportional chambers. The single stage high gain (104) amplifier with FET input has low component count, low cost, and a high packing density of 32 channels per double-sided P. C. board.
openaire +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Design of pixel-level ADCs for energy-sensitive hybrid pixel detectors [PDF]
, 2000 Single-photon counting hybrid pixel detectors have shown\ud to be a valid alternative to other types of X-ray imaging\ud devices due to their high sensitivity, low noise, linear behavior\ud and wide dynamic range.
Nauta, Bram +2 more
core +7 more sources
Radio-frequency operation of a double-island single-electron transistor
, 2004 We present results on a double-island single-electron transistor (DISET) operated at radio-frequency (rf) for fast and highly sensitive detection of charge motion in the solid state.
Bladh K. +7 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A new generation photodetector for astroparticle physics: the VSiPMT [PDF]
, 2014 The VSiPMT (Vacuum Silicon PhotoMultiplier Tube) is an innovative design we proposed for a revolutionary photon detector. The main idea is to replace the classical dynode chain of a PMT with a SiPM (G-APD), the latter acting as an electron detector and ...
BARBARINO, GIANCARLO +11 more
core +2 more sources
Reducing charge-sensitive-amplifier sensitivity to detector capacitance variations
Nuclear Instruments and Methods, 1967 Abstract A method for reducing the sensitivity of charge-sensitive preamplifiers to detector capacitance variations is described. This method is directly applicable to many existing charge-sensitive preamplifiers with only minor modifications.
openaire +2 more sources