Results 61 to 70 of about 1,272,353 (301)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

On magnetic guidance of charged particles

open access: yesPhysics Letters B, 2016
High precision beta decay experiments with polarized neutrons, employing magnetic guiding fields for the decay electrons in combination with energy dispersive detectors, initiated detailed studies of the point spread function (PSF) for homogeneous ...
H. Backe
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Long-Ranged Oppositely Charged Interactions for Designing New Types of Colloidal Clusters

open access: yesPhysical Review X, 2015
Getting control over the valency of colloids is not trivial and has been a long-desired goal for the colloidal domain. Typically, tuning the preferred number of neighbors for colloidal particles requires directional bonding, as in the case of patchy ...
Ahmet Faik Demirörs   +6 more
doaj   +1 more source

THE RADIAL MOTIONS OF CHARGED PARTICLES IN THE FIELD OF THE CHARGED OBJECT IN GENERAL RELATIVITY AND THEIR CLASSIFICATION

open access: yesOdessa Astronomical Publications, 2007
The radial motions of the charged test particles in the field of a spherically symmetric charged object in general relativity are considered and their classification is built.
V. D. Gladush, M. V. Galadgyi
doaj   +1 more source

Forest fires in Europe from July 22-25, 2009 [PDF]

open access: yesArchives of Biological Sciences, 2010
According to the official data of the FAO, in 43% of cases it is unknown how forest fires come about. By analyzing the available data, a hypothesis has been tested according to which such situations are a result of the connection between the burning of ...
Radovanović M.
doaj   +1 more source

Charged Particle Optics Theory [PDF]

open access: yes, 2014
Charged Particle Optics Theory: An Introduction identifies the most important concepts of charged particle optics theory, and derives each mathematically from the first principles of physics.
Groves, Timothy R.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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