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Hematology/Oncology Clinics of North America, 2019 Proton therapy is a form of external beam radiotherapy that has several advantages over conventional photon (x-ray) radiotherapy. Protons are useful in 2 scenarios that apply to a large proportion of cancer patients: lack of exit dose allows for delivery of a therapeutic radiation dose to tumors in challenging anatomic locations, and reduction in ...
Michael J, LaRiviere +3 more
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British Journal of Cancer, 2005 Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation.
Levin, W P +3 more
openaire +2 more sources
Sensitivity analysis of Monte Carlo model of a gantry-mounted passively scattered proton system [PDF]
, 2020 PURPOSE: This study aimed to present guidance on the correlation between treatment nozzle and proton source parameters, and dose distribution of a passive double scattering compact proton therapy unit, known as Mevion S250.
Baradaran-Ghahfarokhi, Milad +4 more
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Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]
, 2014 It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R. +3 more
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Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
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The British Journal of Radiology, 2019 Proton beam therapy is a highly conformal form of radiation therapy, which currently represents an important therapeutic component in multidisciplinary management in paediatric oncology. The precise adjustability of protons results in a reduction of radiation-related long-term side-effects and secondary malignancy induction, which is of particular ...
Thomas, Heike, Timmermann, Beate
openaire +3 more sources
Dose ratio proton radiography using the proximal side of the Bragg peak [PDF]
, 2015 Purpose: In recent years there has been a movement towards single-detector proton radiography, due to its potential ease of implementation within the clinical environment.
A. Gibson +54 more
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Evaluation of resistive-plate-chamber-based TOF-PET applied to in-beam particle therapy monitoring [PDF]
, 2015 Particle therapy is a highly conformal radiotherapy technique which reduces the dose deposited to the surrounding normal tissues. In order to fully exploit its advantages, treatment monitoring is necessary to minimize uncertainties related to the dose ...
Diblen, Faruk +9 more
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Proton-counting radiography for proton therapy: a proof of principle using CMOS APS technology [PDF]
, 2014 Despite the early recognition of the potential of proton imaging to assist proton therapy (Cormack 1963 J. Appl. Phys. 34 2722), the modality is still removed from clinical practice, with various approaches in development. For proton-counting radiography
D J Parker +19 more
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, 2017 Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging.
Bussmann, Michael +5 more
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