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Proton therapy is a form of external beam radiotherapy that has several advantages over conventional photon (x-ray) radiotherapy. Protons are useful in 2 scenarios that apply to a large proportion of cancer patients: lack of exit dose allows for delivery of a therapeutic radiation dose to tumors in challenging anatomic locations, and reduction in ...
Michael J, LaRiviere +3 more
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Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation.
Levin, W P +3 more
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Proton beam therapy (PBT) is an advanced type of radiotherapy that shows a dosimetric advantage over photon beam therapy and provides superior dose distribution. PBT may improve patient survival by improving the local disease control while reducing toxicity to normal organs, which may result in fewer treatment-related complications.
Marija Popovic-Vukovic +4 more
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Background Radical esophagectomy for esophageal squamous cell carcinoma has improved survival, but the rate of recurrence is high. Patients of recurrent esophageal squamous cell carcinoma after failure of chemotherapy have a poor prognosis.
Yojiro Ishikawa +8 more
doaj +1 more source
Background Motion monitoring is essential when treating non-static tumours with pencil beam scanned protons. 4D medical imaging typically relies on the detected body surface displacement, considered as a surrogate of the patient's anatomical changes, a ...
Giovanni Fattori +6 more
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Treatment outcomes of passive scattering proton beam therapy for stage I non-small cell lung cancer
Introduction To investigate the treatment outcomes of passive scattering proton beam therapy using stereotactic ablative radiotherapy (SABR) or hypofractionated radiation therapy (RT) for inoperable patients or those who refused surgery for stage I non ...
Unurjargal Bayasgalan +5 more
doaj +1 more source
Background We performed a prospective phase II study to compare acute toxicity among five different hypofractionated schedules using proton therapy. This study was an exploratory analysis to investigate the secondary end-point of biochemical failure-free
Boram Ha +13 more
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The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy. This article reviews the basic aspects of the physics of proton therapy, including proton interaction mechanisms, proton transport ...
Wayne D, Newhauser, Rui, Zhang
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Objectives: To establish and validate a linear model utilizing diaphragm motion (DM) to predict the displacement of liver tumors (DLTs) for patients who underwent carbon ion radiotherapy (CIRT).
Yao Li BM +5 more
doaj +1 more source
Brachytherapy is an important technique to increase the overall survival of cervical cancer patients. However, a possible shift of the applicators in relation to the target and organs at risk may occur between imaging and treatment.
Byungdu Jo +7 more
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