Results 61 to 70 of about 1,497,667 (293)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Parameters of track structure [PDF]

open access: yes, 1970
Linear energy transfer (or collision stopping power) and energy straggling along the tracks of charged particles are both relevant to the effectiveness of ionizing radiation.
Kellerer, Albrecht M.
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Long-Ranged Oppositely Charged Interactions for Designing New Types of Colloidal Clusters

open access: yesPhysical Review X, 2015
Getting control over the valency of colloids is not trivial and has been a long-desired goal for the colloidal domain. Typically, tuning the preferred number of neighbors for colloidal particles requires directional bonding, as in the case of patchy ...
Ahmet Faik Demirörs   +6 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

THE RADIAL MOTIONS OF CHARGED PARTICLES IN THE FIELD OF THE CHARGED OBJECT IN GENERAL RELATIVITY AND THEIR CLASSIFICATION

open access: yesOdessa Astronomical Publications, 2007
The radial motions of the charged test particles in the field of a spherically symmetric charged object in general relativity are considered and their classification is built.
V. D. Gladush, M. V. Galadgyi
doaj   +1 more source

Forest fires in Europe from July 22-25, 2009 [PDF]

open access: yesArchives of Biological Sciences, 2010
According to the official data of the FAO, in 43% of cases it is unknown how forest fires come about. By analyzing the available data, a hypothesis has been tested according to which such situations are a result of the connection between the burning of ...
Radovanović M.
doaj   +1 more source

Control of Electrostatic Charge on Particles by Impact Charging [PDF]

open access: yesJournal of the Society of Powder Technology, Japan, 2006
The control of electrostatic charge on particles in gas–solids pipe flow has been studied experimentally and theoretically. Alumina particles of 3.3 μm in count median diameter were dispersed in airflow and pneumatically transported in the dilute phase.
Matsusaka, Shuji   +2 more
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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