Results 51 to 60 of about 152,917 (265)
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Control of Electrostatic Charge on Particles by Impact Charging [PDF]
The control of electrostatic charge on particles in gas–solids pipe flow has been studied experimentally and theoretically. Alumina particles of 3.3 μm in count median diameter were dispersed in airflow and pneumatically transported in the dilute phase.
Matsusaka, Shuji +2 more
openaire +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Frictional cooling of positively charged particles
One of the focuses of research and development towards the construction of a muon collider is muon beam preparation. Simulation of frictional cooling shows that it can achieve the desired emittance reduction to produce high-luminosity muon beams. We show
Daniel Greenwald, Allen Caldwell
doaj +1 more source
On fast charged particles scattering in a thin crystalline undulator
The scattering of fast charged particles in a thin silicon crystalline undulator is considered under conditions when all the particles of the beam undergo above-barrier motion with respect to the bent crystalline atomic planes. The consideration is based
N.F. Shul'ga, V.I. Truten'
doaj +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
DIFFRACTIVE SCATTERING OF CHARGED PARTICLES
Studied the scattering of nucleons on nucleons at high energies; studied the angular dependence under the elastic scattering of hadrons. In details considered the scattering of nucleons by deuterons.
E.I. Ismatov, J.K. Ubaev
doaj
The mean volume reflection angle of a high-energy charged particle passing through a bent crystal is expressed as an integral involving the effective interplanar potential over a single crystal period.
M. V. Bondarenco
doaj +1 more source

