Results 101 to 110 of about 710,911 (300)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Charge for Less: An Analysis of Hourly Electricity Pricing for Electric Vehicles

open access: yesWorld Electric Vehicle Journal, 2019
By motivating Electric Vehicle (EV) owners to charge their vehicles when power supply exceeds demand, dynamic pricing can improve system load shape and capacity utilization, reduce consumer costs, and cut pollution.
Jeff Zethmayr, David Kolata
doaj   +1 more source

Characterizing Smartphone Power Management in the Wild

open access: yes, 2016
For better reliability and prolonged battery life, it is important that users and vendors understand the quality of charging and the performance of smartphone batteries. Considering the diverse set of devices and user behavior it is a challenge.
Hoque, Mohammad A., Tarkoma, Sasu
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Leveling the Playing Field: Applying Federal Corporate Charging Considerations to Individuals [PDF]

open access: yes, 2016
The American prison system is grappling with a well-publicized carceral crisis. In the words of former U.S. Attorney General Eric Holder, “too many Americans go to too many prisons for far too long, and for no truly good law enforcement reason.” And, as ...
Amsler, Nicole T.
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

A Corridor-Based Approach to Estimating the Costs of Electric Vehicle Charging Infrastructure on Highways

open access: yesWorld Electric Vehicle Journal, 2019
One of the barriers holding back the large-scale development of electric vehicles is underdeveloped charging infrastructure. The optimal location of charging stations has received much attention, whereas the development of charging infrastructure over ...
Emilia Suomalainen, François Colet
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Research on the UAV-aided data collection and trajectory design based on the deep reinforcement learning

open access: yes物联网学报, 2020
The Internet of things (IoT) era needs to realize the wide coverage and connections for the IoT nodes.However,the IoT communication technology cannot collect data timely in the remote area.UAV has been widely used in the IoT wireless sensor network for ...
Zhiyu MOU   +4 more
doaj  

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