Results 191 to 200 of about 2,176,838 (331)
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
Exploring standard and low luminance visual acuity and the Moorfields Acuity Chart as outcome measures in inherited retinal disease. [PDF]
Taylor LJ, Josan AS, MacLaren RE.
europepmc +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
Charts of the Horizontal Components of the Mean Surface Wind Over the Oceans for January and July [PDF]
C. L. Jordan
openalex +1 more source
This study developed a nitrogen‐strengthened copper‐iron‐zinc (N‐CuFeZn) alloy bioactive dressing integrated with electromagnetic stimulation. The coaxial dressing, made from 0.04 mm filaments with 1120 MPa tensile strength, showed that electromagnetic activation enhanced therapeutic outcomes by increasing VEGF expression, promoting angiogenesis (2.1 ...
Xiaohui Qiu+9 more
wiley +1 more source
The Fetal Region-specific Optimized Growth Standard (FROGS)-A fetal and birthweight centile calculator validated in a national population. [PDF]
Pritchard NL+11 more
europepmc +1 more source
Graphical Determination of Path Curves on Psychrometric Chart in Dehumidification and Water Cooling.
Hikoji Inazumi
openalex +2 more sources