Results 1 to 10 of about 267,219 (299)
Recent applications of computational methods to allosteric drug discovery
Frontiers in Molecular Biosciences, 2023 Interest in exploiting allosteric sites for the development of new therapeutics has grown considerably over the last two decades. The chief driving force behind the interest in allostery for drug discovery stems from the fact that in comparison to ...
Rajiv Gandhi Govindaraj +4 more
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Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers
Nature Communications, 2022 SMARCA2 has been identified as a synthetic lethal target in SMARCA4 mutated tumors, however, homology between the two has hindered the development of selective SMARCA2 inhibitors.
Jennifer Cantley +28 more
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Frontiers in Neurology, 2022 BackgroundIn recent years, there has been an increasing number of publications on Meniere's disease. However, there are no bibliometric research on Meniere's disease.
Wujun Zou +3 more
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Suicides on the Austrian railway network: hotspot analysis and effect of proximity to psychiatric institutions [PDF]
Royal Society Open Science, 2017 Railway suicide is a significant public health problem. In addition to the loss of lives, these suicides occur in public space, causing traumatization among train drivers and passengers, and significant public transport delays.
Markus J. Strauss +3 more
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Intraurban NO2 hotspot detection across multiple air quality products
Environmental Research Letters, 2023 High-resolution air quality data products have the potential to help quantify inequitable environmental exposures over space and across time by enabling the identification of hotspots, or areas that consistently experience elevated pollution levels ...
Anastasia Montgomery +6 more
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Diversity, 2023 The frequency of cetacean strandings is increasing, with multiple causes identified. We examined temporal and spatial trends in stranding numbers along the coastal areas of the East China Sea from 1990 to 2021.
Shaobo Yang +3 more
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Proceedings of the Conference on Empirical Methods in Natural Language Processing - EMNLP '08, 2008 Compared to the telephone, email based customer care is increasingly becoming the preferred channel of communication for corporations and customers. Most email-based customer care management systems provide a method to include template texts in order to reduce the handling time for a customer's email.
Srinivas Bangalore, David Smith
openaire +2 more sources
Low-activity hotspot investigation method via scanning using deep learning
Frontiers in Energy Research, 2022 Small areas of elevated activity are a concern during a final status scan survey of residual radioactivity of decommissioned and contaminated sites.
Junwoo Bae +6 more
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Frontiers in Microbiology, 2023 BackgroundAntibiotic resistance is one of the main global threats to human health, and just the development of new antimicrobial medications is not enough to solve the crisis.
Zulipikaer Maimaiti +9 more
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Frontiers in Pediatrics, 2023 BackgroundThis study aims to analyze the research hotspots, evolution, and developing trends in pediatric bronchiectasis over the past 20 years using bibliometric analysis and visualization tools to identify potential new research directions ...
Ting Gong +6 more
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