Results 11 to 20 of about 138 (76)
Association of alcohol consumption with all-cause mortality, new-onset stroke, and coronary heart disease in patients with abnormal glucose metabolism-Findings from a 10-year follow-up of the REACTION study. [PDF]
J Diabetes, 2023 Highlights This long‐term longitudinal study demonstrates the association between alcohol consumption and health outcomes in patients with abnormal glucose metabolism including type 2 diabetes mellitus and prediabetes. Occasional drinking (less than once a week) reduces the risk of all‐cause mortality, while heavy alcohol consumption (≥30 g/day for men
Cui M +7 more
europepmc +2 more sources
Journal of Diabetes, Volume 15, Issue 11, Page 968-977, November 2023., 2023 Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li +9 more
wiley +1 more source
A Review of micro RNAs changes in T2DM in animals and humans miRNAs在2型糖尿病人类和动物中的变化
Journal of Diabetes, Volume 15, Issue 8, Page 649-664, August 2023., 2023 Highlights MicroRNAs (miRNAs) are overexpressed in inflammation, insulin resistance, and type 2 diabetes mellitus (T2DM). Many types of miRNAs are changed during the T2DM progression. miRNAs have a potential role as a biomarker in T2DM diagnosis. Abstract Type 2 diabetes mellitus (T2DM) and its associated complications have become a crucial public ...
Mohammad Reza Afsharmanesh +3 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 1, Page 14-22, July 2023., 2023 ABSTRACT Objective A favorable postnatal prognosis in cases of pulmonary atresia/critical stenosis with intact ventricular septum (PA/CS‐IVS) is generally equated with the possibility of achieving biventricular (BV) repair. Identification of fetuses that will have postnatal univentricular (UV) circulation is key for prenatal counseling, optimization of
C. Villalaín +9 more
wiley +1 more source
Associations between posttraumatic stress and stroke: A systematic review and meta‐analysis
Journal of Traumatic Stress, Volume 36, Issue 2, Page 259-271, April 2023., 2023 Abstract The objective of the present study was to systematically review the existing literature for studies examining the association between posttraumatic stress disorder (PTSD) and stroke risk and perform a meta‐analysis to obtain a pooled risk estimate describing the association.
Hely D. Nanavati +3 more
wiley +1 more source
Journal of Advanced Nursing, Volume 76, Issue 12, Page 3528-3536, December 2020., 2020 Abstract Aim To explore experiences of peer support among parents of children with congenital heart defects. Design A study analysing written responses to open‐ended questions about peer support, collected via an online survey distributed in Sweden. Methods Respondents were recruited during 3 months in 2018 by means of convenience sampling, through ads
Tommy Carlsson +2 more
wiley +1 more source
HoxC5基因内2个SNP位点与单纯性先天性心脏病的关联研究
Zhongguo shiyan zhenduanxue, 2004 目的在前期工作定位的人类单纯性先天性心脏病易感区域12q131～133内,选取HoxC5基因内2个已知单核苷酸多态（SNP）rs2071448、rs2071450,检测其在单纯性CHD患者和正常人群中的分布情况,分析其与单纯性CHD的相关性。方法应用变性高效液相色谱法（DHPLC）结合测序分析108名单纯性先天性心脏病患者及200名正常人2个SNP位点基因型,应用χ2检验统计分析患者组和对照组基因型频率及等位基因频率。结果编码区SNP位点rs2071448未检测到多态;位于HoxC5基因3 ...
宫立国 +4 more
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焦虑抑郁障碍对女性冠心病患者血清CA125和TNF-α表达的影响
Zhongguo shiyan zhenduanxue, 2019 冠状动脉疾病是临床最常见的心血管疾病,其中冠心病（CHD）是冠状动脉疾病最严重的临床表现,也是全世界最常见的死因[1]。在美国,2011年共有375295人死于CHD,大约每分钟有24人发病和1人死亡[2]。CHD主要是由多基因遗传变异和环境因素共同导致的严重疾病[3]。目前,冠状动脉造影,心脏磁共振扫描,血清/血浆生物标志物等已经被广泛应用于CHD的诊断[4]。CHD快速精确的诊断能够明显改善病人预后和生活质量。许多因素与CHD发病有关,包括血浆脂质浓度、血压、吸烟、糖尿病和炎症标志物等[5 ...
刘永政, 郜琳, 王倩
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基于CHD基因和EE0.6基因遗传多态鉴定白枕鹤、丹顶鹤性别研究报告
野生动物学报, 2018 白枕鹤(Grus vipio)和丹顶鹤(Grus japonensis)是中国重点保护动物,为单态性鸟,很难通过外观和形态来进行性别鉴定,给人工繁殖造成很大困难。研究已发现CHD基因和EE0.6序列片段大小在非平胸鸟类W、Z染色体上均存在差异。基于此,本研究以无锡市动物园饲养的白枕鹤和丹顶鹤为研究对象,经PCR实验,对白枕鹤和丹顶鹤CHD基因和EE0.6序列的相关片段进行了特异性扩增。结果显示,这2种方法PCR扩增结果一致,并根据这一结果进行白枕鹤、丹顶鹤配对,均成功孵化出后代,表明该PCR鉴定结果可靠,
孙志明 徐 琪 徐 禄 倪谷音 王金美
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脂联素启动子基因多态性和脂联素水平与高血压及并发症的相关性研究
Zhongguo shiyan zhenduanxue, 2008 目的观察血清脂联素（APN）水平及APN基因启动子区域单核苷酸多态性（SNP）频率与高血压（HP）及其合并症间的相关性,探讨脂联素基因（aPM1）多态性与HP及合并症间的遗传危险因素。并确立一种高效、准确、经济的检测APN基因实用筛查方法,供临床检测应用。方法对单纯HP组（1组）、HP合并T2DM（HP-T2DM）组（2组）、HP合并冠心病（H-CHD）组（3组）、HP合并肾病（HP-NE）组（4组）和对照组（5组）分别测定空腹血清APN及生化指标。采用变性高效液相色谱（DHPLC）技术 ...
贾玫 +5 more
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