Results 71 to 80 of about 1,216,970 (284)

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Biobased biodegradable chelating agents enhance coupled ex situ and in situ carbon dioxide mineralization via peridotite dissolution and wormholing

Communications Earth & Environment
Mantle peridotite, which is also present in near-surface environments, reacts readily with CO2, and is expected to be suitable for CO2 mineralization.
Luis Salalá, Noriaki Watanabe, Jiajie Wang, Atsushi Okamoto   +3 more
doaj   +1 more source

Effect of FA/O Chelating Agent on Copper Ion Removing on Silicon Surface

, 2011
Along with the feature size reducing and the increase of integration level rapidly in ULSI，the request for metal impurities contamination on silicon substrate surface appears specially rigorous.
Yan Gang He, Bao Hong Gao, Yu Ling Liu, Xin Huan Niu, Bai Mei Tan   +4 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

STUDIES REGARDING THE CHELATE-INDUCED HYPERACCUMULATION OF CU AND FE USING LOLIUM PERENNE SPECIES IN MINING AREAS

Scientific Papers Animal Science and Biotechnologies, 2023
The plant capacity to absorb high amounts of metal for a short period of time is the major factor that influences the efficiency of phytoextraction. The hyperaccumulating plants uptake high amounts in their tissues correlated to the metal concentrations ...
ANCA-DIANA PRICOP, B. LIXANDRU, SMARANDA MÂŞU, C. BOGATU, SZIDONIA SZUCS   +4 more
doaj  

NUMERICAL MODEL FOR CHELATING AGENTS ENHANCED SOIL FLUSHING

, 2015
“In situ” remediation technologies, if applied without careful evaluation of the process parameters, may themselves be a source of pollution. The soil flushing is a useful technology for in situ remediation of a heavy metal contaminated soil and is ...
MARTORELLI, ELISA, VIOTTI, Paolo, ANTONUCCI, ANGELA, LUCIANO, ANTONELLA, LAMBERTI, MAFALDA, MANCINI, GIUSEPPE, TORRETTA, VINCENZO   +6 more
core  

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Preparation and Preliminary Biological Evaluation of 177Lu Labelled Rituximab

Journal of Isotopes, 2014
For evaluating whether 177Lu-Rituximab could be applied for radioimmunoimaging and radioimmunotherrapy of non-Hodgkin’s Lymphoma， Rituximab, a specific chimeric monoclonal antibody used in CD20-positive B-cell Non-Hodgkin’s Lymphoma, was conjugated to ...
MA Xiu-feng1;ZHANG Jun-li2;LI Hong-yu1,2;LIANG Ji-xin1;YANG Yun2;YANG Chun-hui2;DU Jin1,3
doaj   +1 more source

Agent fabrication and its implementation for agent-based electronic commerce [PDF]

, 2002
In the last decade, agent-based e-commerce has emerged as a potential role for the next generation of e-commerce. How to create agents for e-commerce applications has become a serious consideration in this field.
Guan, SU, Zhu, F
core   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source