Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator [PDF]
Molecules, 2021 Deferoxamine B is an outstanding molecule which has been widely studied in the past decade for its ability to bind iron and many other metal ions.
Denise Bellotti +2 more
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Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation [PDF]
ChemistryOpenPolymeric systems are used in clinical settings to bind small molecules and ions. They show advantages in pharmacokinetics and reduced side effects compared to low‐molecular‐weight agents.
Roberta Panebianco +2 more
doaj +3 more sources
Deferoxamine-Based Materials and Sensors for Fe(III) Detection [PDF]
Chemosensors, 2022 Deferoxamine (DFO) is a siderophore widely studied for its ability to bind iron(III) strongly. Thanks to its versatility, it is suitable for several clinical and analytical applications, from the recognized iron(III) chelation therapy to the most recent ...
Raffaela Biesuz +2 more
exaly +4 more sources
Deferoxamine Compensates for Decreases in B Cell Counts and Reduces Mortality in Enterovirus 71-Infected Mice [PDF]
Marine Drugs, 2014 Enterovirus 71 is one of the major causative agents of hand, foot and mouth disease in children under six years of age. No vaccine or antiviral therapy is currently available.
Bai Lin +2 more
exaly +4 more sources
Deferoxamine Modulates Corneal Endothelial Cell Biological Properties Associated with Increased VEGF Expression [PDF]
MedicinaBackground and Objectives: The objective of this study is to evaluate whether deferoxamine modulates cell biological properties, such as proliferation and wound closure of porcine corneal endothelial cells (CECs) in vitro, and whether the treatment of ...
Barbara Sophie Brunner +5 more
doaj +2 more sources
Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis [PDF]
Neural Regeneration Research, 2019 Ferroptosis is an iron-dependent novel cell death pathway. Deferoxamine, a ferroptosis inhibitor, has been reported to promote spinal cord injury repair.
Xue Yao +14 more
doaj +2 more sources
Restoring the Angiogenic Capacity of the Human Diabetic Adipose-derived mesenchymal stem cells Primed with Deferoxamine as a Hypoxia Mimetic Agent: Role of HIF-1α [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Insufficient angiogenesis is associated with serious diabetic complications. Recently, adipose-derived mesenchymal stem cells (ADScs) are known to be a promising tool causing therapeutic neovascularization.
Raziye Tajali +4 more
doaj +1 more source
The Role of Deferoxamine and Quercetin on The Short Term Chronic Toxicity of Iron on The Pituitary, Ovaries and Uterus of Prepubertal Albino Rats [PDF]
Zagazig Journal of Forensic Medicine and Toxicology, 2020 Iron is an important metal for Hypothalamic-pituitary-gonadal axis. Deferoxamine used as a potent antioxidant plus its chelating function. Quercetin is an effective antioxidant and also reported to have estrogenic activities. The aim of this study was to
Omnia Megahed +3 more
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An overview of complications associated with deferoxamine therapy in thalassemia [PDF]
Journal of Nephropharmacology, 2021 Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei +5 more
doaj +1 more source
Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. [PDF]
PLoS Pathogens, 2015 Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae.
Mingfu Liu +8 more
doaj +1 more source