Deferoxamine Modulates Corneal Endothelial Cell Biological Properties Associated with Increased VEGF Expression [PDF]
MedicinaBackground and Objectives: The objective of this study is to evaluate whether deferoxamine modulates cell biological properties, such as proliferation and wound closure of porcine corneal endothelial cells (CECs) in vitro, and whether the treatment of ...
Barbara Sophie Brunner +5 more
doaj +2 more sources
Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator
Molecules, 2021 Deferoxamine B is an outstanding molecule which has been widely studied in the past decade for its ability to bind iron and many other metal ions.
Denise Bellotti, Maurizio Remelli
exaly +3 more sources
Deferoxamine-Based Materials and Sensors for Fe(III) Detection
Chemosensors, 2022 Deferoxamine (DFO) is a siderophore widely studied for its ability to bind iron(III) strongly. Thanks to its versatility, it is suitable for several clinical and analytical applications, from the recognized iron(III) chelation therapy to the most recent ...
Raffaela Biesuz +2 more
exaly +3 more sources
Restoring the Angiogenic Capacity of the Human Diabetic Adipose-derived mesenchymal stem cells Primed with Deferoxamine as a Hypoxia Mimetic Agent: Role of HIF-1α [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Insufficient angiogenesis is associated with serious diabetic complications. Recently, adipose-derived mesenchymal stem cells (ADScs) are known to be a promising tool causing therapeutic neovascularization.
Raziye Tajali +4 more
doaj +1 more source
The Role of Deferoxamine and Quercetin on The Short Term Chronic Toxicity of Iron on The Pituitary, Ovaries and Uterus of Prepubertal Albino Rats [PDF]
Zagazig Journal of Forensic Medicine and Toxicology, 2020 Iron is an important metal for Hypothalamic-pituitary-gonadal axis. Deferoxamine used as a potent antioxidant plus its chelating function. Quercetin is an effective antioxidant and also reported to have estrogenic activities. The aim of this study was to
Omnia Megahed +3 more
doaj +1 more source
An overview of complications associated with deferoxamine therapy in thalassemia [PDF]
Journal of Nephropharmacology, 2021 Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei +5 more
doaj +1 more source
Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis
Neural Regeneration Research, 2019 Ferroptosis is an iron-dependent novel cell death pathway. Deferoxamine, a ferroptosis inhibitor, has been reported to promote spinal cord injury repair.
Xue Yao +14 more
doaj +1 more source
Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. [PDF]
PLoS Pathogens, 2015 Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae.
Mingfu Liu +8 more
doaj +1 more source
Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017 [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Background: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world.
Ali hassan Rahmani +2 more
doaj +1 more source
Effect of Deferoxamine on Rat Fetal Bone Formation and on it is Certain Regulating Genes
Kufa Journal for Veterinary Medical Sciences, 2021 The aim of this study is to investigate the deferoxamine effect on rat fetal bone formation and on certain regulating genes expression that play a vital key role in bone formation.
Abeer Esmael Thanoon +1 more
doaj +1 more source