Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. [PDF]
PLoS Pathogens, 2015 Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae.
Mingfu Liu +8 more
doaj +4 more sources
Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator
Molecules, 2021 Deferoxamine B is an outstanding molecule which has been widely studied in the past decade for its ability to bind iron and many other metal ions.
Denise Bellotti, Maurizio Remelli
exaly +3 more sources
Deferoxamine-Loaded Chitosan-Based Hydrogel on Bone Implants Showing Enhanced Bond Strength and Pro-Angiogenic Effects [PDF]
Journal of Functional BiomaterialsAngiogenesis is vital for bone fracture healing and plays a significant role in the fate of orthopedic implants. The growth and maintenance of new blood vessels at the fracture site of patients is essential, which promotes the clinical outcome of plasma ...
Huan Liu +5 more
doaj +2 more sources
Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation [PDF]
ChemistryOpenPolymeric systems are used in clinical settings to bind small molecules and ions. They show advantages in pharmacokinetics and reduced side effects compared to low‐molecular‐weight agents.
Roberta Panebianco +2 more
doaj +2 more sources
Restoring the Angiogenic Capacity of the Human Diabetic Adipose-derived mesenchymal stem cells Primed with Deferoxamine as a Hypoxia Mimetic Agent: Role of HIF-1α [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Insufficient angiogenesis is associated with serious diabetic complications. Recently, adipose-derived mesenchymal stem cells (ADScs) are known to be a promising tool causing therapeutic neovascularization.
Raziye Tajali +4 more
doaj +1 more source
Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide. [PDF]
Front PharmacolTawfiq RA +3 more
europepmc +3 more sources
An overview of complications associated with deferoxamine therapy in thalassemia [PDF]
Journal of Nephropharmacology, 2021 Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei +5 more
doaj +1 more source
Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis
Neural Regeneration Research, 2019 Ferroptosis is an iron-dependent novel cell death pathway. Deferoxamine, a ferroptosis inhibitor, has been reported to promote spinal cord injury repair.
Xue Yao +14 more
doaj +1 more source
Journal of Pharmaceutical Health Care and Sciences, 2023 Background Erythrocyte transfusion is an indispensable component of supportive care after hematopoietic stem cell transplantation (HSCT). However, HSCT recipients are susceptible to the development of acute kidney injury (AKI) with multifactorial causes.
Hirokazu Nakayama +4 more
doaj +1 more source
Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017 [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Background: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world.
Ali hassan Rahmani +2 more
doaj +1 more source